Advances in Food Technology and Nutritional Sciences · Vol. 4, No. 2 · 2018 · pp. e13–e16 · e-ISSN 2377-8350

Leptin Activates NLRP3 Inflammasome-Associated with Type II Diabetes and Obesity

Reagan Cauble, Shaimaa Hamad, Ellen Herring, Callan Lichtenwalter, Clayton McGuire, Sami Dridi

DOI: https://doi.org/10.17140/aftnsoj-4-e016 · Published 2018-10-23 · Licence: https://creativecommons.org/licenses/by/4.0 · © 2018 The Author(s)

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Abstract

Obesity is a major health problem worldwide and is often associated with leptin resistance and inflammation.1 In this editorial, we will briefly describe the leptin system and the (NOD)-like receptor protein 3 (NLRP3) inflammasome and dis-cuss recent discoveries related to their interaction and role in the development of metabolic disease mainly obesity and Time-divi-sion multiplexing (TDM).

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