Diabetes Research · Vol. 4, No. 1 · 2018 · pp. 9–11 · e-ISSN 2379-6375

More Significant Life for Diabetic Patients in the Perspectives of Anti-Aging

Hiroshi Bando

Tokushima University and Medical Research, Nakashowa 1-61, Tokushima 770-0943, JapanJapan

DOI: https://doi.org/10.17140/droj-4-137 · Published 2018-07-27 · Licence: https://creativecommons.org/licenses/by/4.0 · © 2018 The Author(s)

Abstract

For the patients with diabetes, basal daily lifestyle would be considered in the light of meal, exercise, rest, alcohol intake, smoking and oral health. These six factors are from the concept as a basic direction of “Health Japan 21” for comprehensive implementation of national health promotion.1 Satisfactory control of lifestyle can lead to protection and treatment of diabetes and successful anti-aging. From this implication, to check up physical and mental condition would be important and helpful in clinical practice. Concerning Anti-Aging Medicine (AAM), Kahn and Rowe formerly initiated in 1980-90’s, proposing successful aging. After that, AAM has been developed in the world for decades until today.2,3 Currently, clinical importance of AAM includes not only to maintain healthy condition and to protect diseases, but also to promote activities of daily living (ADL) and quality of life (QoL), leading to long and significant lives.4 Furthermore, adequate judgement and development of AAM would be also considered in the light of medical, social, economical, and ethical aspects

OpenJournal PUBLISHERS Opinion More Significant Life for Diabetic Patients in the Perspectives of Anti-Aging * Hiroshi Bando, MD, PhD, FACP* Tokushima University and Medical Research, Nakashowa 1-61, Tokushima 770-0943, Japan * *Corresponding author Hiroshi Bando, MD, PhD, FACP Instructor, Tokushima University and Medical Research, Nakashowa 1-61, Tokushima 770-0943, Japan; Tel. +81-90-3187-2485; Fax: +81-88-603-1030; E-mail: pianomed@bronze.ocn.ne.jp Article information th th th Received: July 26 , 2018; Accepted: July 27 , 2018; Published: July 27 , 2018 Cite this article Bando H. More significant life for diabetic patients in the perspectives of anti-aging. Diabetes Res Open J. 2018; 4(1): 9-11. doi: 10.17140/DROJ-4-137 For the patients with diabetes, basal daily lifestyle would be con- today for years. One of the famous questionnaire would be short sidered in the light of meal, exercise, rest, alcohol intake, smoking form-36 (SF-36), including international version and also Japanese and oral health. These six factors are from the concept as a basic version.7 In addition, there were several questionnaire about QoL, direction of “Health Japan 21” for comprehensive implementa- including World health Organization (WHO)/QOL-26, WHO-5 tion of national health promotion.1 Satisfactory control of lifestyle Well-Being Index, cognitive function and five-level version of the 8-11 can lead to protection and treatment of diabetes and successful EuroQoL five-dimensional questionnaire.8-11 Indeed, these ques- anti-aging. From this implication, to check up physical and mental tionnaires have showed meaningful method and result, but rather condition would be important and helpful in clinical practice. complicated tendency were observed. Compared to these, Anti- Aging QoL Common Questionnaire (AAQoL) seems to be useful Concerning Anti-Aging Medicine (AAM), Kahn and for its convenience taking only about a few minutes. Rowe formerly initiated in 1980-90’s, proposing successful aging. After that, AAM has been developed in the world for decades until The AAQoL consists of more than 50 items of physical 2,3 today.2,3 Currently, clinical importance of AAM includes not only and mental symptoms, and six lifestyle items. For each question, to maintain healthy condition and to protect diseases, but also to subjects can answer in simple way by 5-point scale (1. None, 2. promote activities of daily living (ADL) and quality of life (QoL), Little, 3. Mild, 4. Moderate, 5. Severe).12 leading to long and significant lives.4 Furthermore, adequate judge- ment and development of AAM would be also considered in the Regarding the studies for AAQoL, authors have contin- light of medical, social, economical, and ethical aspects.5 ued various analyses for years. Formerly, each item in AAQoL was statistically calculated for investigation. Authors have proposed In order to obtain optimal daily life, the status of QoL new method for analysis. Its way is to categorize several items into and ADL have to be evaluated by adequate method. As for AAM, one group with totally several categorization.13 After some trials, several aspects would be necessary to evaluate, such as dietary and we proposed exam method for 8 categories with 7 physical and exercise habit, nutrition, physical activity, resting, alcohol, smoking mental items each.

and dental health. These factors are pointed out for national health promotion by the Ministry of Heath, Labour and Welfare of Ja- Taking this method into consideration, we investigated pan.6 It has been known as the “National Health Promotion Move- subjects and patients with various situations and diseases. They st ment in the 21st Century (Health Japan 21)” as the third health included patients with chronic renal failure and hemodialysis, sub- 14,15 promotion measure for citizens since 2000.

jects with masters athletes in ice-skating and athletics. A variety of questionnaires for QoL were proposed until There were several impressive data to mention from the cc Copyright 2018 by Bando H. This is an open-access article distributed under Creative Commons Attribution 4.0 International License (CC BY 4.0), which allows to copy, redistribute, remix, transform, and reproduce in any medium or format, even commercially, provided the original work is properly cited. Diabetes Res Open J. 2018; 4(1): 9-11. doi: 10.17140/DROJ-4-137 results concerning masters athletes. Their exercise habits seemed to AAQoL Questionnaire and some points recommended to modify. be stable, which was mostly 3-4 days a week constantly throughout Regarding the future direction, to select adequate items into focus the year. As to the lifestyle, too much eating is rare, the frequency and to compare with other QoL rating scales would be continued of drinking is rather high, but the amount of drinking is low, and for further investigation. Regarding to managing and handing the opportunity of communicate to others is frequent. When age and health status QoL scores, it would be necessary to collect much gender were matched and compared with the control group, mas- data from enough number of samples, and to develop fair and ters athletes showed significantly lower physical and psychological highly transparent discussion involving a large number of medical symptoms.

From these way of living and lifestyle, masters athletes In summary, clinical significance of AAQoL for AAM 14,15 suggested to have positive and happier life. Thus, application have been described in this article. It is convenient and useful for of AAQoL to various clinical research studies would be useful and clinical practice and research, as well as health and medical checkup expected to obtain the meaningful results of mutual relationship in in various situations.20 Moreover, AAQoL is beneficial for other the light of physical, mental, and social aspects. area, such as cosmetics, food and medicine, exercise and sports, and health industry. As AAM is developing in broader fields, Concerning the circumstances at the birth of AAQoL, AAQoL is expected to be applied to further extent in a variety of medical care situation was deeply affected at that time. It was just occasion, leading to successful aging. Furthermore, successful ag- when AAM was introduced to Japan from United States, when ing will provide more significant and meaningful life to the diabetic expectations and needs for AAM was recognized in medical field. patients.

Under such circumstances, debates on the influence of aging for various symptoms were accumulated.

References

  1. The Ministry of Health, Labour and Welfare, Japan. Health form of the items were developed reflecting health condition of Japan 21. A Basic Direction for Comprehensive Implementation people with 20-80 years old.16 Specifically, symptoms are roughly of National Health Promotion, 2013. https://www.mhlw.go.jp/ divided into two categories which are physical symptoms and psyfile/06-Seisakujouhou-10900000-Kenkoukyoku/0000047330.pdf chological symptoms, as well as lifestyle habits. AAQoL includes not only items from medicine and health, but also items from so-
  2. KahnRL. On “Successful aging and well-being: self-rated comcial aspect, in which items and features are commonly used for pared with Rowe and Kahn”. Gerontologist. 2002; 42(6): 725-726. research in occupational hygiene.17
  3. RoweJWKahnRL. Successful aging 2.0: Conceptual expan-The beneficial point of AAQoL has been simple, consions for the 21st century. J Gerontol B Psychol Sci Soc Sci. 2015; 70(4): venient and useful. Therefore, AAQoL has been used for clini- 593-596. doi: 10.1093/geronb/gbv025 cal practice, clinical research study, and also medical and/or health checkup for usual people. It has been developed which has been10.1093/geronb/gbv025 https://doi.org/10.1093/geronb/gbv025
  4. MartinPKellyNKahanaB. Defining successful aging: A performed and developed widely for long years in Japan. Espetangible or elusive concept? Gerontologist. 2015; 55(1): 14-25. doi: cially, AAM medical and health checkup is called in Human Dock 10.1093/geront/gnu044 in Japan. It can focus on evaluating degree of impaired function in any organ system by utilizing AAQoL Questionnaire.1810.1093/geront/gnu044 https://doi.org/10.1093/geront/gnu044
  5. WhitleyEBenzevalMPophamF. Associations of successful aging with socioeconomic position across the life-course. J Aging Continuous development includes the further research Health. 2016; 898264316665208. doi: 10.1177/0898264316665208 of AAQOL for its usefulness and effectiveness which are from 18,19 much data in thousands of subjects10.1177/0898264316665208 https://doi.org/10.1177/0898264316665208
  6. The Ministry of Health, Labour and Welfare, Japan. Measures against Lifestyle-Related Diseases through “Health Japan 21” and Recently, AAQoL Questionnaire itself was studied in de-Promotion of “Shokuiku (food and nutrition education)”, 2008. tail. Using AAQoL, lifestyles and functional ages, more than 6000 https://www.mhlw.go.jp/english/wp/wp-hw2/part2/p2c1s3.pdf cases were investigated. The correlations of 5 age factors (muscle, bone, hormone, nerve, blood vessel) and 10 symptoms were inves-
  7. Fukuhara S, Ware JE Jr, Kosinski M, Wada S, Gandek B. Psychotigated.19 Ten symptoms include 5 physical factors (ocular sympmetric and clinical tests of validity of the Japanese SF-36 Health toms, palpitations/shortness of breath, gastrointestinal problems, Survey. J Clin Epidemiol. 1998; 51: 1045-1053. stiffness, weight problems) and 5 mental factors (depression, mental anxiety, mental confusion, insomnia and emotional anxiety)
  8. Pace-SchottEFSpencerRM. Age-related changes in the cogni-As the results, detail influencing correlations were found 4 factors tive function of sleep. Prog Brain Res. 2011; 191: 75-89. with lifestyle, 5 factors with body, and 5 factors with mind.19
  9. IkedaSShiroiwaTIgarashiA. Developing a Japanese version Furthermore, the results showed the validity of the of the EQ-5D-5L value set. J Natl Inst Public Health. 2015; 64: 47-Diabetes Res Open J. 2018; 4(1): 9-11. doi: 10.17140/DROJ-4-137 55. 15. Bando H, Nakamura T, Yonei Y, Takenaka Y, Seki K. Lipid profile of masters athletes in ice-skating, a model of anti-aging10.17140/droj-4-137 https://doi.org/10.17140/droj-4-137
  10. Topp CW, Østergaard SD, Søndergaard S, Bech P. The WHO-5 research. Glycative Stress Research. 2015; 2(2):52-57. doi: 10.24659/ Well-Being Index: A systematic review of the literature. Psychother gsr.2.2_052 Psychosom. 2015; 84(3): 167-176. doi: 10.1159/000376585 16. Yonei Y, Mizuno Y, Orimo H, et al. Effect of eletro-potential https://doi.org/10.1159/000376585
  11. ShiroiwaTIkedaSNotoS. Comparison of value set therapy on symptoms associated with QOL and aging. Anti-Aging based on DCE and/or TTO data: Scoring for EQ-5D-5L Health Medicine. 2003; 2: 16-23. States in Japan. Value Health. 2016; 19(5): 648-654. doi: 10.1016/j. jval.2016.03.1834 17. Uno B. Effective utilization of questionnaires in regular medical checkups. Occupational Health Management (Rodo Eisei Kan-10.1016/j.jval.2016.03.1834 https://doi.org/10.1016/j.jval.2016.03.1834
  12. YoneiYTakahashiYWatanabeM. Effects on the human ri) [in Japanese]. 2001; 12: 45-51. body of a dietary supplement containing l-carnitine and Garcinia cambogia extract: A study using double-blind tests. J Clin Biochem 18. Yonei Y, Takabe W. Aging assessment by anti-aging medical Nutr. 2008; 42: 89-103. checkup. Health Evaluation and Promotion. 2015; 42: 459-464
  13. BandoHYoshiokaTYoneiYNakamuraT. Investigation of 19. Oguma Y, Iida K, Yonei Y, Satoh T. Significance evaluation of quality life in athletes from an anti-aging perspective. Primary Care Anti-Aging QOL Common Questionnaire. Glycative Stress Research. Japan. 2006; 4(1): 47-51. 2016; 3 (3): 177-185. doi: 10.24659/gsr.3.3_17710.24659/gsr.3.3_177 https://doi.org/10.24659/gsr.3.3_177
  14. BandoHTakenakaYNakamuraTKounoikeKYoneiY. In- 20. Yabukita H, Miyazaki R, Nomoto K, et al. Characteristics of vestigation for Quality of Life (QOL) and self-esteem for health in physical functions in elderly people requiring support. Anti-Aging masters’ athletes. Glycative Stress Research. 2015; 2 (4): 174-181. doi: Medicine. 2013; 10: 16-20. 10.24659/gsr.2.4_17410.24659/gsr.2.4_174 https://doi.org/10.24659/gsr.2.4_174