Diagnostic Advances in Acute Viral Meningitis: Any Novelty for the Physician?

Ozgur Karcioglu, Ebru Yilmaz

Emergency Physician, Department of Emergency Medicine, University of Health Sciences, Istanbul Education and Research Hospital, Istanbul,TurkeyTurkey
Emergency Physician, Deptartment of Emergency Medicine, Nizip Community Hospital, Gaziantep,TurkeyTurkey

DOI: https://doi.org/10.17140/emoj-4-150 · Published 2019-01-07 · Licence: https://creativecommons.org/licenses/by/4.0 · © 2019 The Author(s)

Also available as PDF (figures and tables appear in the PDF).

Keywords: Acute viral meningitis; Aseptic meningitis; Acute viral encephalitis; Central nervous system infection; Diagnosis; Lumbar puncture

Conclusion

cells. In Herpetic AVE, red blood cells are proportional to the degree of frontal/temporal damage. Interestingly, CSF lactate levels AVM is an outstanding emergency which can lead to morbidity and are proportional to the number of red blood cells found in CSF. mortality all over the world. Findings in blood and CSF work-up after a clinical index of suspicion result in a high yield of diagnosis. Next-generation sequencing (NGS) is the diagnostic mo- Technological advances should be coupled with clinical findings dality of choice to screen for viral deoxyribo nucleic acid (DNA) to produce accurate clinical management in the target population. in CSF in cases with strong suspicion for AVM or AVE.30

Conflicts Of Interest

Polymerase chain reaction (PCR) is used to diagnose herpetic meningeal involvement. Of note, identification of HSV The authors declare that they have no conflicts of interest. DNA in the CSF by PCR is of diagnostic value in herpetic meningoencephalitis.7 In patients with AVE due to viruses with a CSF

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