Coronary CT Angiography in Coronary Artery Disease: from Diagnosis to Prevention

Abstract

Coronary CT angiography has emerged as reliable imaging tool for the diagnosis of
coronary artery disease. Coronary CT angiography has the ability to demonstrate excellent
visualization of anatomical changes in coronary artery with high diagnostic value in the detection
of lumen stenosis or occlusion, and characterization of coronary plaque composition.
Furthermore, coronary CT angiography offers prognostic value in the prediction of adverse
cardiac events. Although coronary CT angiography is limited to the assessment of coronary
anatomy and lumen changes, coronary CT angiography-derived computer modeling and hemodynamic
analysis has the potential to evaluate functional significance of coronary artery
disease. This review article aims to provide an overview of both diagnostic and prognostic
value of coronary CT angiography in coronary artery disease. Limitations of coronary CT
angiography are briefly discussed, while functional assessment of coronary artery disease
with use of coronary CT angiography-generated coronary artery models is highlighted.