Internal Medicine · Vol. 7, No. 1 · 2024 · pp. e1–e3 · e-ISSN 2572-9233

Functional Relationship of Serum Sodium with Heart Patients

Mahashweta Das, Rabindra N. Das

Department of History,The University of Burdwan, Burdwan,West Bengal 713104, IndiaIndia
Department of Statistics,The University of Burdwan, Burdwan,West Bengal 713104, IndiaIndia

DOI: https://doi.org/10.17140/imoj-7-e003 · Published 2024-01-05 · Licence: https://creativecommons.org/licenses/by/4.0 · © 2024 The Author(s)

Also available as PDF (figures and tables appear in the PDF).

Abstract

Serum sodium (SNa) is one of the principal extracellular fluid electrolytes that is necessary for balancing extracellular fluid volume and potentials across cell membranes.1,2 SNa’s imbalances in concentrations have been recognized to manifest as headaches, nausea, restlessness, and confusion, while rapid changes in Na concentrations result in acute neurologic symptoms such as impaired mental status and seizures.

Acknowledgment

The authors are very grateful to the principal data investigators, who provided the data freely for scientific study.

Conflict Of Interest

The authors declare that they have no conflicts of interest.

References

  1. ShrimankerIBhattaraiS. Electrolytes. Treasure Island (FL), USA: StatPearls Publishing; 2020
  2. TerryJ. The major electrolytes: Sodium, potassium, and chloride. J Intraven Nurs. 1994; 17(5): 240-247
  3. SahayMSahayR. Hyponatremia: A practical approach. Indian J Endocrinol Metab. 2014; 18(6): 760-771. doi: 10.4103/2230- 8210.14132010.4103/2230-8210.141320 https://doi.org/10.4103/2230-8210.141320
  4. UpadhyayAJaberBLMadiasNE. Incidence and prevalence of hyponatremia. Am J Med. 2006; 119(7 Suppl 1): S30-S35. doi: 10.1016/j.amjmed.2006.05.00510.1016/j.amjmed.2006.05.005 https://doi.org/10.1016/j.amjmed.2006.05.005
  5. FunkGCLindnerGDrumlW. Incidence and prognosis of dysnatremias present on ICU admission. Intensive Care Med. 2010; 36 (2): 304-311. doi: 10.1007/s00134-009-1692-010.1007/s00134-009-1692-0 https://doi.org/10.1007/s00134-009-1692-0
  6. SicaDA. Hyponatremia and heart failure--pathophysiology and implications. Congest Heart Fail. 2005; 11: 274-277. doi: 10.1111/j.1527-5299.2005.04180.x10.1111/j.1527-5299.2005.04180.x https://doi.org/10.1111/j.1527-5299.2005.04180.x
  7. FarmakisDFilippatosGParissisJ. Hyponatremia in heart failure. Heart Fail Rev. 2009; 14: 59-63. doi: 10.14797/mdcj-13-1-4010.14797/mdcj-13-1-40 https://doi.org/10.14797/mdcj-13-1-40
  8. FilippatosTDElisafMS. Hyponatremia in patients with heart failure. World J Cardiol. 2013; 5: 317-328
  9. LoridoJCAGómezJCFormigaF. Hyponatremia as predictor of worse outcome in real world patients admitted with acute heart failure. Cardiol J. 2013; 20: 506-512. doi: 10.5603/ CJ.2013.0136
  10. GheorghiadeMRossiJSCottsW. Characterization and prognostic value of persistent hyponatremia in patients with se vere heart failure in the ESCAPE trial. Arch Intern Med. 2007; 167: 1998-2005. doi: 10.1001/archinte.167.18.199810.1001/archinte.167.18.1998 https://doi.org/10.1001/archinte.167.18.1998
  11. SotoNSGheorghiadeMKajimotoK. Hyponatremia and in-hospital mortality in patients admitted for heart failure (from the ATTEND registry). Am J Cardiol. 2013; 111: 1019-1025. doi: 10.1016/j.amjcard.2012.12.01910.1016/j.amjcard.2012.12.019 https://doi.org/10.1016/j.amjcard.2012.12.019
  12. KomoriTEguchiKSaitoTHoshideSKarioK. Riser pattern is a novel predic tion of adverse events in heart failure patients with preserved ejection fraction. Circ J. 2017; 81: 220-226. doi: 10.1253/circj.CJ-16-074010.1253/circj.cj-16-0740 https://doi.org/10.1253/circj.cj-16-0740
  13. GheorghiadeMAbrahamWTAlbertNM. Relationship between admission serum sodium concentration and clinical out comes in patients hospitalized for heart failure: An analysis from the OPTIMIZE-HF registry. Eur Heart J. 2007; 28: 980-988. doi: 10.1093/eurheartj/ehl54210.1093/eurheartj/ehl542 https://doi.org/10.1093/eurheartj/ehl542
  14. AhmadTMunirABhattiSHAftabMRazaMA. Survival analysis of heart failure patients: A case study. PLoS One. 2017; 12(7): e0181001. doi: 10.1371/journal.pone.018100110.1371/journal.pone.0181001 https://doi.org/10.1371/journal.pone.0181001
  15. UC Irvine. Heart failure clinical records. Website. https:// archive.ics.uci.edu/ml/datasets/Heart+failure+clinical+records. Accessed November 30, 2023
  16. LeeYNelderJAPawitanY. Generalized Linear Models with Random Effects. 2nd ed. London, UK: Chapman & Hall; 2017. e3Editorial | Volume 7 | Number 1 | Submit your article to this journal | https://openventio.org/submit-manuscript/