Cardiovascular Disease and NASH
Keywords:
NAFLD: Non-alcoholic fatty liver disease, CVD: Cardiovascular disease, MetS: Metabolic Syndrome, AF: Atrial Fibrillation, CAC: Coronary Artery Calcium, CT: Computed Tomography, FFAs: Free Fatty Acids, NASH: Non alcoholic steatohepatitis, LDL-C: Low-density Lipoprotein-Cholesterol, HMGCR: HMG CoA Reductase, VLDL: Very-low-density lipoprotein, CAD: Coronary Artery DiseaseAbstract
Non-alcoholic fatty liver disease (NAFLD) and Non-alcoholic steatohepatitis (NASH) are associated with cardiovascular events and Metabolic Syndrome (MetS). NAFLD is considered to be a hepatic manifestation of MetS and has become an important public health issue because of its high prevalence. It is currently being considered an independent Cardiovascular disease (CVD) risk factor. In this clinical review, we will briefly review the mechanisms linking NAFLD to the complement system, endothelial dysfunction and the atherosclerosis.
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