Cardiovascular Disease and NASH

Authors

  • Erika Rabelo Forte de Siqueira
  • Leila Maria Moreira Beltrao Pereira
  • Arun Jayant Sanyal

Keywords:

NAFLD: Non-alcoholic fatty liver disease, CVD: Cardiovascular disease, MetS: Metabolic Syndrome, AF: Atrial Fibrillation, CAC: Coronary Artery Calcium, CT: Computed Tomography, FFAs: Free Fatty Acids, NASH: Non alcoholic steatohepatitis, LDL-C: Low-density Lipoprotein-Cholesterol, HMGCR: HMG CoA Reductase, VLDL: Very-low-density lipoprotein, CAD: Coronary Artery Disease

Abstract

Non-alcoholic fatty liver disease (NAFLD) and Non-alcoholic steatohepatitis (NASH) are associated with cardiovascular events and Metabolic Syndrome (MetS). NAFLD is considered to be a hepatic manifestation of MetS and has become an important public health issue because of its high prevalence. It is currently being considered an independent Cardiovascular disease (CVD) risk factor. In this clinical review, we will briefly review the mechanisms linking NAFLD to the complement system, endothelial dysfunction and the atherosclerosis.

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Published

2015-07-29

Issue

Vol. 1 No. 2 (2015): Volume 1 Issue 2 2015

Section

Articles