Otolaryngology · Vol. 2, No. 5 · 2016 · pp. 156–157 · e-ISSN 2470-4059

The Asessment of Gastroesophageal and Gastropharyngeal Reflux Prevelance After Total Laryngectomy

İmran Aydoğdu, Zeynep Aydoğdu, Ziya Salturk, Yavuz Uyar

Okmeydanı Training and Research Hospital, ENT Clinic, Istanbul, TurkeyTurkey

DOI: https://doi.org/10.17140/otloj-2-132 · Published 2016-10-27 · Licence: https://creativecommons.org/licenses/by/4.0 · © 2016 The Author(s)

Also available as PDF (figures and tables appear in the PDF).

Abstract

Objective: The aim of this study is to detect prevalence of glomerular filtration rate (GFR) in total laryngectomy patients. Method: Thirty-eight healthy patients who underwent total laryngectomy and followed at least 6 months paticipated to study. Patients were asked to complete gastroesophageal reflux disease questionnaire (GerdQ) and examined with flexible laryngoscopy. Result: Twenty-seven of 38 (71%) patients had scores over 8 and diagnosed as gastroesophageal reflux (GER). Eleven patients had scores lower than 8. Conclusion: Our study revealed that GER and GFR incidence are higher in total laryngectomy patients.

Keywords: Laryngectomy; Gastropharyngeal reflux (GFR); Gastroesophageal reflux (GER)

Introduction

Gastroesophageal reflux (GER) is a condition in which gastrointestinal content passes through upper esophageal sphincter and reaches esophagus. This situation is called GER disease when casues signs and symptoms.1 Gastropharyngeal reflux (GFR) is an advanced situation that gastrointestinal content reaches pharyngeal mucosa passing through upper esophageal sphincter.2 It has been proved that GFR is associated with numerous otorhinolaryngological diseases including otitis media with effusion, laryngeal granuloma and subglottic stenosis. It is accused 3,4 of being one of the etiological factors in esophageal carcinoma.3,4 GFR usually exhibits itself without gastrointestinal symptoms.5 It should be considered in chronic otorhinolaryngological problems.6

Although its importance has been accepted in otorhinolaryngological problems it was not studied in detail at laryngectomized patients. GFR may cause pharyngocutanous fistula and voice problems in laryngectomized patients.7 We aimed to study prevalence of GFR in total laryngectomy patients.

Methods

We evaluated 38 healthy patients who underwent total laryngectomy and followed at least 6 months. All participants were informed of the study procedures and signed a consent form.

(mean±standard deviation). Student t-tests were used for comparison data of pre-operation and ISSN 2470-4059

Results

GerdQ has high sensitivity and specifity in GER patients and scores over 8 was accepted as GER.9 Thirty-four males and 4 females were included in the study. Mean age of the patients were 59.8±73.27 of 38 (71%) patients had scores over 8 and diagnosed as GER. Eleven patients had scores lower than 8. There was a statistically significant difference between patients with higher scores and lower scores than 8 (p=0.024).

Conclusion

Our study revealed that GER and GFR incidence are higher in total laryngectomy patients. This can be related to physiological changes which were caused by surgery. Diagnosis and treatment of these patients are important because it negatively affects quality-of-life (QoL). Due to above reported facts we recommend prophylactic proton pump inhibitor use after total laryngectomy.

Conflicts Of Interest

The authors declare that they have no conflicts of interest.

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