Department of ENT, Eskisehir City Hospital, Eskisehir, TurkeyTurkey
Department of ENT, Yunus Emre Government Hospital, Eskisehir, TurkeyTurkey
Near East Unıversıty, Nicosia, CyprusCyprus
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Aim To examine the role of the Identafi® device in early diagnosis of the nature of oral lesions. Results Buccal mucosal lesions that diagnosed Kreatosis were the most seem lesion in oral area. Conclusion It has been observed that the indentative device provides convenience to the physician in the early diagnosis of precancerous oral lesions and some tissue formations that may be overlooked can be reached.
Keywords: Identafi®; Oral lesion; Precancerous; Early diagnosis; Tobacco; Alcohol
Buccal mucosal lesions that diagnosed Kreatosis were the most seem lesion in oral area.
It has been observed that the indentative device provides convenience to the physician in the early diagnosis of precancerous oral lesions and some tissue formations that may be overlooked can be reached.
® Identafi®; Oral lesion; Precancerous; Early diagnosis; Tobacco; Alcohol.
ral cancers; It is a type of cancer that has been diagnosed with lesions in areas such as the floor of the mouth (under O 1-3 the tongue), lips, gums, tongue, inner faces of cheeks, palate. Its Mortality rate has increased significantly in recent years.4,5
® Identafi® is an feasible, ancillary, veiling equipment aspecting three distinct flashes that are practiced subsequently to explore oral ornaments. In addition to a flash transmitting diode (light-emitting diode (LED)) white flash, the equipment also contains violet flash of 405 nm wavelength and a 545 nm wavelength green-amber flash. The violet and green-amber flashes activate ornament fluorescence and reflectance spectroscopy variously.
Looking at the early diagnosis statistics of oral cancer, it is seen that it creates serious differences in terms of survival.6 Although there is a great responsibility for doctors in early diagnosis, some problems that vary from patient to patient can make early diagnosis difficult.7 Based on these problems, we conducted
cc Copyright 2020 by Fidan V. This is an open-access article distributed under Creative Commons Attribution 4.0 International License (CC BY 4.0), which allows ® this study, which examined the role of the Identafi® device in early diagnosis, on cases we observed suspicious on cases in Eskişehir and encountered remarkable results.
4,5 The aim of this study is to provide early diagnosis of precancerous oral lesions in the mouth and to determine how it will affect the ® prognosis in early diagnosis by testing the Identafi® device that will help the physician for this purpose.
The present study included the patients whom applied to Otorhinolaryngology Department of Yunus Emre Goverment Hospital and City Hospital of Eskişehir between 2011-2019. An initial oral screening was done by otorhinolaryngologists and dentists. The ® suspected cases were subjected to Identafi® Oral cancers sreening device.
Otolaryngol Open J. 2020; 6(1): 8-10. doi: 10.17140/OTLOJ-6-161
This device is designed for light; it uses the energy it broadcasts at different wavelengths by combining it with different reflection feature between malignant and bening tissue. The device, by its design, has many features that will make it easier to scan the restrictive oral area. Thus, the findings required for early diagnosis can be easily detected even in hard-to-reach areas.
The identification device has been tested in cases of suspected suspicion and numerical data have been obtained that can be classified according to cigarette, alcohol, spicy food use, age and gender, oral location (Tables 1, 2, 3, 4, 5 and 6).
Table 1. Distribution of Study Table 2. Distribution of Subjects Subjects by Gender Based on Consumption of Smoke
Male 284 (47.3) Smoker 48 (8) Female 317 (52.7) Non-smoker 553 (92) Total 601 (100) Total 601 (100)
Distribution of Subjects
Table 3. Lesion Type n (%) Based on Consumption of Alcohol
User 284 (47.3) Non-user 317 (52.7) Total 601 (100)
Table 5. Distribution of Study Subjects Based on the Site of the Lesions
Palate 2 (0.4) Floor of mouth 1 (0.2) Tongue 25 (4.2) Buccal mucosa 573 (95.2) Total 601 (100)
Table 6. Distribution of Study Subjects Based on the Site of the Lesions
Tobacco user 45 3 0.001 14.310 Tobacco nonuser 7 546 Alcohol user 23 4 0.001 9.612 Alcohol nonuser 2 572
The conclusion of this study; it has been observed that the indentative device provides convenience to the physician in the early diagnosis of precancerous oral lesions and some tissue formations 8,9 that may be overlooked can be reached.8,9
There liability of the device would depend upon further 8,9 studies which can reveal its specificity and sensitivity.8,9 The effectiveness of this devise when proved and reduction of the cost of the device would make it a popular and common screening tool among dentists and dental schools in the detection of oral cancer in the community. Studies have shown a strong relationship between the use of tobacco and alcohol in the development of 6-9 precancerous lesions.6-9 This study also presents that tobacco was a capable prognosticator for improvement of precancerous lesions.
® The gains of the Identafi® equipment is it is modest, firm extent deuced with a twisted diagnosis reflector which grants customers to obviously observe tough-to-grasp fields, such as beneath the tongue, and behind of the pharynx.
The government authorities should provide training to rural health workers to enable them to screen patients for oral precancerous lesions and refer them for biopsy and further management at higher centres. The health authorities should provide
Table 4. Distribution of Study regular health education on the hazards of tobacco use to school Subjects by Gender children thereby deterring them from adopting the habit of tobac- co use. Leukoplakia 149 (24.8)
Erythroplakia 8 (1.3)
Lichen planus 217 (36.1) Fibrosis 165 (27.5) The authors declare that they have no conflicts of interest. Keratosis 209 (34.8) Total 601 (100) REFERENCES
1. Agha-Hosseini F, Sheykhbahaei N, SadrZadeh-Afshar MS. Evaluation of potential risk factors that contribute to malignant transformation of oral lichen planus: A literature review. J ContempDent Pract. 2016; 17(8): 692-701.
2. Rivera C, Zandonadi FS, Sánchez-Romero C, Soares CD, Granato DC, González-Arriagada WA, et al. Agrin has a pathological role in the progression of oral cancer. Br J Cancer. 2018; 118(12): 1628-1638. doi: 10.1038/s41416-018-0135-5
3. George B, Sebastian ST, Soman RR, Mulamoottil VM, Johny MK. Prevalence of precancerous lesions in an adult population. Indian J Dent Res. 2019; 30(4): 500-505. doi: 10.4103/ijdr.IJDR_138_18
4. Ballivet de Régloix S, Badois N, Bernardeschi C, Jouffroy T, Hofmann C. Risk factors of cancer occurrence after surgery of oral intraepithelial neoplasia: A long-term retrospective study. Laryngoscope. 2018; 128(11): 2546-2551. doi: 10.1002/lary.27214
5. Nadeau C, Kerr AR. Evaluation and management of oral potentially malignant disorders. Dent Clin North Am. 2018; 62(1): 1-27. doi: 10.1016/j.cden.2017.08.001
6. Ye X, Zhang J, Tan Y, Chen G, Zhou G. Meta-analysis of two computer-assisted screening methods for diagnosing oral precancer and cancer. Oral Oncol. 2015; 51(11): 966-975. doi: 10.1016/j. oraloncology.2015.09.002 Otolaryngol Open J. 2020; 6(1): 8-10. doi: 10.17140/OTLOJ-6-161
7. Goodson ML, Sloan P, Robinson CM, Cocks K, Thomson PJ. Oral precursor lesions and malignant transformation--who, where, what, and when? Br J Oral Maxillofac Surg. 2015; 53(9): 831-835. doi: 10.1016/j.bjoms.2015.08.268
8. Lalla Y, Matias M, Farah CS. Oral mucosal disease in an Austral- Submit your article to this journal | https://openventio.org/submit-manuscript/ ian urban Indigenous community using autofluorescence imaging and reflectance spectroscopy. Aust Dent J. 2015; 60(2): 216-224. doi: 10.1111/adj.12320
9. Huber MA. Adjunctive diagnostic aids in oral cancer screening: an update.Tex Dent J. 2012; 129(5): 471-480.