Obesity Research · Vol. 3, No. 1 · 2016 · pp. 20–22 · e-ISSN 2377-8385

Coenzyme Q10, Glucose Homeostasis and the Probable Mediating Role of Adipokines

Mohammad Javad Hosseinzadeh-Attar, MD, PhD, Elham Alipoor, MSc, Parvaneh Mehrdadi, MSc

DOI: https://doi.org/10.17140/oroj-3-e008 · Published 2016-04-25 · Licence: https://creativecommons.org/licenses/by/4.0 · © 2016 The Author(s)

Also available as PDF (figures and tables appear in the PDF).

Abstract

Coenzyme Q10 is one of the most popular nutritional supplements, which has been discovered in 1955. It is also known as ubiquinone, Q10, CoQ and vitamin Q10. This coenzyme has two isoforms; the oxidized form, ubiquinone, is an electron carrier in mitochondrial respiratory chain and the reduced form, ubiquinol, acts as an antioxidant.1,2 Studies reported its beneficial effects in some diseases such as diabetes, heart failure, hypertension, and Parkinson disease.3,4 Q10 has also been proposed to be helpful in prevention and treatment of neurodegenerative and mitochondrial related diseases.5 Q10 could potentially be effective on metabolic disorders including lipid profile, blood pressure, glycemic control and insulin resistance in different diseases

Keywords: diabetes, heart failure, hypertension, and Parkinson disease

Acknowledgment

The authors appreciate Tehran University of Medical Sciences for their full support.

Conflicts Of Interest

Dr. Hosseinzadeh-Attar has nothing to disclose.

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