A Couple’s Personalized-Care Intervention for Weight-Loss and Diabetes based on DNA and Gut Biome Profiles: A Case Study

Abstract

Introduction
The global prevalence of obesity has reached epidemic proportions. Given the negative strain that obesity and associated chronic
diseases, such as type 2 diabetes, put on the healthcare system and the economy, disease management has begun evolving to help
individuals change their behaviors. Obesity is often difficult to treat and even harder to maintain. Past studies have failed to show
weight loss maintenance over long periods after interventions. To overcome the complexity of obesity, a multifaceted precision care
treatment approach should be adopted.
Aim
The aim of this case study was to assess the health benefits and weight loss journey of a cohabiting Caucasian heterosexual married
couple using the Digbi Health personalized obesity management program. A personalized integrative nutrition plan is created based
on one’s genetic and gut microbiome obesity risk profile and incorporates daily digital tracking and lifestyle coaching. Never before
has a program offered personalized data including genetic, gut microbiome and lifestyle coaching to help people understand the best
plan to lose weight and keep it off long term.
Method
The male subject achieved a total change in weight loss of 15.94%, as well as a reduction in A1C and blood pressure levels and the
female subject achieved a 13.65% change in weight loss over a period of four months. The couple have still been able to maintain
their weight loss goals four months after completing the program, stating their individual and personalized approach gave them the
tools long-term to maintain.
Conclusion
A supportive environment for cohabiting couples following a personalized weight loss program based on their genetic and gut microbiome profile may help with weight loss and long-term maintenance.