Coenzyme Q10, Glucose Homeostasis and the Probable Mediating Role of Adipokines

Abstract

Coenzyme Q10 is one of the most popular nutritional supplements, which has been discovered
in 1955. It is also known as ubiquinone, Q10, CoQ and vitamin Q10. This coenzyme has two
isoforms; the oxidized form, ubiquinone, is an electron carrier in mitochondrial respiratory
chain and the reduced form, ubiquinol, acts as an antioxidant.1,2 Studies reported its beneficial
effects in some diseases such as diabetes, heart failure, hypertension, and Parkinson disease.3,4
Q10 has also been proposed to be helpful in prevention and treatment of neurodegenerative
and mitochondrial related diseases.5
Q10 could potentially be effective on metabolic disorders
including lipid profile, blood pressure, glycemic control and insulin resistance in different diseases