Psychology and Cognitive Sciences · Vol. 5, No. 2 · 2019 · pp. 50–52 · e-ISSN 2380-727X

An Urgent Request for Evidence-Based Mental Health Intervention Research in Low-Income and Middle-Income Countries

Linda E. O’Raw, Zara Tariq

Division of Psychiatry and Applied Psychology, University of Nottingham, School of Medicine, Nottingham NG7 2TU, UKUnited Kingdom
Muslim Hands, Nottingham, UKUnited Kingdom

DOI: https://doi.org/10.17140/pcsoj-5-149 · Published 2019-11-13 · Licence: https://creativecommons.org/licenses/by/4.0 · © 2019 The Author(s)

Abstract

The rise in mental health issues is a global phenomenon. The World Health Organisation (WHO) has published data that shows the global burden of mental disorders continues to grow and claim that the health systems throughout the world are struggling to respond adequately to the needs of people with mental health disorders.1 Approximately 85% of the world population resides in 153 low-income and middle-income countries (LMICs). Further, more than 80% of people who have mental disorders are located in LMICs.2 However, it is estimated that 90-95% of mental health resources, including human resources for psychological therapies are being delivered in countries that only account for 5% of the population.3 This is a global inequity and it is unjust. This article serves as a desperate call to researchers to urgently engage in evidence-based psychological therapies interventions in LMICs. This is not as an attempt to reallocate existing provision of mental health resources, but to reduce the treatment gap by advocating opportunities for all.

PSYCHOLOGY AND COGNITIVE SCIENCES PUBLISHERS ISSN 2380-727X Open Journal An Urgent Request for Evidence-Based Mental Health Intervention Research in Low-Income and Middle-Income Countries Linda E. O’Raw, BSc, PhD1*, Zara T ariq, BSc2 1Division of Psychiatry and Applied Psychology, University of Nottingham, School of Medicine, Nottingham NG7 2TU, UK 2Muslim Hands, Nottingham, UK *Corresponding author Linda E. O’Raw, BSc, PhD Mental Health Researcher, Division of Psychiatry and Applied Psychology, University of Nottingham, School of Medicine, Nottingham NG7 2TU, UK; T el. +44 (0)115 7484098, Ext. 84245; E-mail: Linda.O’raw@nottingham.ac.uk Article information Received: October 30th, 2019; Revised: November 10th, 2019; Accepted: November 12th, 2019; Published: November 13th, 2019 Cite this article O’Raw LE, Tariq Z. An urgent request for evidence-based mental health intervention research in low-income and middle-income countries. Psychol Cogn Sci Open J. 2019; 5(2): 50-52. doi: 10.17140/PCSOJ-5-149 Short Communication Short Communication | Volume 5 | Number 2 | 50 Copyright 2019 by O’Raw LE. This is an open-access article distributed under Creative Commons Attribution 4.0 International License (CC BY 4.0), which allows to copy, redistribute, remix, transform, and reproduce in any medium or format, even commercially, provided the original work is properly cited. cc T he rise in mental health issues is a global phenomenon. The World Health Organisation (WHO) has published data that shows the global burden of mental disorders continues to grow and claim that the health systems throughout the world are strug - gling to respond adequately to the needs of people with mental health disorders.1 Approximately 85% of the world population re- sides in 153 low-income and middle-income countries (LMICs). Further, more than 80% of people who have mental disorders are located in LMICs.2 However, it is estimated that 90-95% of men- tal health resources, including human resources for psychological therapies are being delivered in countries that only account for 5% of the population.3 This is a global inequity and it is unjust. This article serves as a desperate call to researchers to urgently engage in evidence-based psychological therapies interventions in LMICs. This is not as an attempt to reallocate existing provision of mental health resources, but to reduce the treatment gap by advocating opportunities for all.

Mental health disorders are the leading cause of disability worldwide as measured in disability adjusted life years (DALYs), accounting for nearly a quarter (22%) of all days lived with disa- bility.4 As populations age, the burden of non-communicable dis- eases, such as mental disorders, is rising. Mental and neurological disorders combined account for over a third (37%) of the disability burden associated with chronic non-communicable diseases.5 The DALYs due to mental illness grew by 38% in the twenty years between 1990 and 2010.4 That growth is expected to continue, be- cause mental disorders are most commonly diagnosed in the adult years, and as populations age, they become more susceptible to neurological disorders such as dementia and Parkinsonism. Inter - estingly, the WHO (2011) predicted that, by 2030, mental health problems, particularly depression, will be the leading cause of mortality and morbidity globally. 1 Currently, more than 300 mil- lion people suffer from depression globally and it contributes to 800,000 suicides per year.1 Depression alone is likely to be the third leading cause of disease burden in low-income countries and the second highest cause of disease burden in middle-income coun- tries.6 There is a clear association between the mental health of a child and the development of mental health disorders as an adult.1,7,8 Mental health issues are estimated to affect 10-20% of youth in LMICs, 9 although this statistic is thought to be highly conservative as it fails to take account of any co-variation of fac - tors, such as lack of supply side barriers or demand side barriers. Further, confounding factors like the normalisation each individ- ual society has placed on the impact of stressful life events and experiences will have a significant bearing on how mental health is seen, the stigma attached to it and how statistical information is recorded and interpreted.7,10 Interestingly, between 1992 and 2001, published research from LMICs contributed just 5% of the mental health research-related articles to the internationally indexed liter - ature on mental health.10 However, despite this clear and apparent need, evidence-based research and sustainable interventions for children and adolescence with mental health issues as well as the aging populations in LMICs are restricted and limited.2-4,7 Stressful trigger events that are associated with an in- crease in mental health disorders are often very different in LMICs than high-income countries (HICs). For example, children and ad- olescents in LMICs that have experienced either man-made (such as civil conflict or war) or natural disasters (such as flooding or O’Raw LE et al Psychol Cogn Sci Open J. 2019; 5(2): 50-52. doi: 10.17140/PCSOJ-5-149 drought), are at greater risk from a variety of mental health is- sues, the most common of which are elevated anxiety and mood disorders, suicide and suicidal ideation, acute stress reactions in- cluding post-traumatic stress disorders, sleep disruption, as well as a decreased sense of self and identity from loss (of place or person) and grief reactions.10-13 Interestingly, neuroscience research has comprehensively documented that prolonged exposure to the stress hormone, cortisol, can damage areas of the brain associated with memory, movement and mental health.14 Therefore, it is hard- ly surprising that suicide rates in a number of LMICs are some of the highest in the world.8,13 Stigma is a known factor that inhibits access to psycho - logical therapies. About 8 in 10 people with depression had expe- rienced discrimination, usually within familiar settings such as with family members, friends, work relationships, marriage and divorce and with other interpersonal relationships. 6 Nearly forty percent of people with depression will not reach out for things they tru- ly consider important in their personal and work life, out of fear (anticipated stigma) that they may be discriminated against. 6 This hinders progress, as the tendency is to hide family members with mental illness out of embarrassment, rather than bring them for - ward to access the treatment and care they need. Such individuals are thus, often at increased risk of suffering human rights abus- es. Therefore, in the author’s opinion, those that engage with evi - dence-based intervention research should include a programme of mental health awareness training to aid the ongoing sustainability of that intervention.

Despite huge strides in recent years, the treatment gap remains enormous and represents a gross inequity that exists with people’s ability to access mental health provisions in LMICs. The most vulnerable groups appear to be child and adolescent and the aging populations, although the data available from various government statistics are lacking and there is little on the ground evidence-based intervention research being published that shows sustainable steps forward. The associated consequence of this is critical gaps in knowledge and a failure to adequately understand global mental health needs, especially in poorer socioeconomic countries. Given the growing burden of mental health across the globe and an increasing population size, both high-income coun- tries as well as LMICs could benefit from the identification of successful, low-cost sustainable evidence-based interventions, par- ticularly those that include the family and community-based pro - visions. As global citizens, academic researchers and clinicians, we have a responsibility to address this global injustice and inequity, ensuring that mental health provision is available to those in need by developing sustainable interventions.

CONFLICTS OF INTEREST The authors declare that they have no conflicts of interest.

References

  1. World Health Organisation (WHO). Mental Health Action Plan 2013-2020. Web site. https://www.who.int/mental_health/publications/action_plan/en/. Accessed October 29, 2019
  2. JacobKSharanPMirzaI. Mental health systems in countries: Where are we now? Lancet. 2007; 370: 1061-1077. doi: 10.1016/S0140-6736(07)61241-010.1016/s0140-6736(07)61241-0 https://doi.org/10.1016/s0140-6736(07)61241-0
  3. PatelVXiaoSChenH. The magnitude of and health system responses to the mental health treatment gap in adults in India and China. Lancet. 2016; 388: 3074-3084. doi: 10.1016/ S0140-6736(16)00160-4
  4. LimSSVosTFlaxmanAD. A comparative risk assess ment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990-2010: A systematic analysis for the Global Burden of Disease Study 2010. Lancet. 2013; 280: 2224-2260. doi: 10.1016/S0140-6736(12)61766-810.1016/s0140-6736(12)61766-8 https://doi.org/10.1016/s0140-6736(12)61766-8
  5. BloomDECafiero-FonsecaETMcGovernME. The macroeconomic impact of non-communicable diseases in China and India: Estimates, projections, and comparisons. The Journal of the Economics of Ageing. 2014; 4: 100-111. doi: 10.1016/j. jeoa.2014.08.00310.1016/j.jeoa.2014.08.003 https://doi.org/10.1016/j.jeoa.2014.08.003
  6. LasalviaAZoppeiSVan BortelT. Global pattern of experienced and anticipated discrimination reported by people with major depressive disorder: A cross-sectional survey. Lancet. 2013; 9860: 55-62. doi: 10.1016/S0140-6736(12)61379-810.1016/s0140-6736(12)61379-8 https://doi.org/10.1016/s0140-6736(12)61379-8
  7. Global Forum for Health Research, World Health Organisation (WHO). Research capacity for mental health in low- and middle-income countries: Results of a mapping project. https://www. who.int/mental_health/MHRC_FullText.pdf. Accessed October 29, 2019
  8. UddinRBurtonNWMapleMKhanSRKhanA. Suicidal ideation, suicide planning, and suicide attempts among adolescents in 59 low-income and middle-income countries: A population-based study. Lancet Child Adolesc Health. 2019; 3: 223-233. doi: 10.1016/ S2352-4642(18)30403-6
  9. KielingCBaker-HenninghamHBelferM. Child and adolescent mental health worldwide: Evidence for action. Lancet. 2011; 378: 1515-1525. doi: 10.1016/S0140-6736(11)60827-110.1016/s0140-6736(11)60827-1 https://doi.org/10.1016/s0140-6736(11)60827-1
  10. SaxenaSParajeGSharanPKaramGSadanaR. The 10/90 divide in mental health research: Trends over a 10-year period. Br J Psychiatry. 2006; 188: 81-82. doi: 10.1192/bjp.bp.105.01122110.1192/bjp.bp.105.011221 https://doi.org/10.1192/bjp.bp.105.011221
  11. PatelVArayaRChatterjeeS. Treatment and prevention of mental disorders in low-income and middle-income countries. Lancet. 2007; 370: 991-1004. doi: 10.1016/S0140-6736(07)61240-910.1016/s0140-6736(07)61240-9 https://doi.org/10.1016/s0140-6736(07)61240-9
  12. VibhakarVAllenLRGeeBMeiser-StedmanR. A systematic review and meta-analysis on the prevalence of depression in children and adolescents after exposure to trauma. Journal of Affective Short Communication | Volume 5 | Number 2 |51 O’Raw LE et al Psychol Cogn Sci Open J. 2019; 5(2): 50-52. doi: 10.17140/PCSOJ-5-149 Disorders. 2019; 255: 77-89. doi: 10.1016/j.jad.2019.05.00510.17140/pcsoj-5-149 https://doi.org/10.17140/pcsoj-5-149
  13. KoyanagiAOhHCarvalhoAF. Bullying victimization and suicide attempt among adolescents aged 12-15 years from 48 countries. J Am Acad Child Adolesc Psychiatry. 2019; 58: 907-918. doi: 10.1016/j.jaac.2018.10.01810.1016/j.jaac.2018.10.018 https://doi.org/10.1016/j.jaac.2018.10.018
  14. HaynesLEGriffithsMRHydeREBarberDJMitchellIJ. Dexamethasone induces limited apoptosis and extensive sublethal damage to specific subregions of the striatum and hippocampus: Implications for mood disorders. Neuroscience. 2001; 104(1): 57-69. doi: 10.1016/s0306-4522(01)00070-7 52Short Communication | Volume 5 | Number 2 | Submit your article to this journal | https://openventio.org/submit-manuscript/10.1016/s0306-4522(01)00070-7 https://doi.org/10.1016/s0306-4522(01)00070-7