Hyperhomocysteinemia and Alcoholism: A Double Hit?

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Authors

  • Bashir M. Rezk Department of Natural Sciences, Southern University at New Orleans, New Orleans, LA 70126, USA
  • Pamela A. Lucchesi Department of Basic Sciences, Geisinger Commonwealth School of Medicine, Medical Sciences Building, Scranton, PA 18509, USA

DOI:

https://doi.org/10.17140/TFMOJ-2-123

Keywords:

Homocysteine (HCY), neural tube defects (NTD), hyperhomocysteinemia (HHCY)

Abstract

Homocysteine (HCY) is a non-protein sulfur-containing amino acid. It has received a great deal of attention over the last two decades within the scientific community for its unique role in the induction of several diseases ranging from atherosclerotic cardiovascular
disease to neural tube defects (NTD). The hypothesis that hyperhomocysteinemia (HHCY) causes atherosclerosis was proposed by McCully1 in 1969, when he observed that children with homocysteinuria had atherosclerotic plaques of the peripheral, coronary, and cerebral vasculature.

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Published

2017-12-22

How to Cite

Bashir M. Rezk, & Pamela A. Lucchesi. (2017). Hyperhomocysteinemia and Alcoholism: A Double Hit?. Toxicology and Forensic Medicine, 2(2), 84–87. https://doi.org/10.17140/TFMOJ-2-123

Issue

Vol. 2 No. 2 (2017): Volume 2 Issue 2 2017

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