A Case Report on Vogt-Koyanagi-Harada Disease Seen at a Tertiary Hospital in the Philippines

Abstract

Vogt-Koyanagi-Harada disease (VKHD) is a defined as a bilateral granulomatous panuveitis that affects pigmented structures, such as the eye, inner ear, meninges, skin and hair. Up until this point, the exact pathogenesis is still a matter of inquiry. The most accepted mechanism involves autoimmune reaction among tissues that contains melanocytes. This disease
has been described to have four stages: prodromal, acute uveitic, convalescent and chronic/recurrent stage, all of which affecting pigmented structures in the body. Early diagnosis and meticulous use of steroids has remained as the mainstay treatment, however, poor prognosis for individuals who presented with complications in the initial consultation has been associated with a poor final visual acuity. The main objective of presenting this classic case of Vogt-Koyanagi-Harada disease is
describing its chronic systemic course, and the possible medical and surgical management for the disease and its complications.