Glaucoma Diagnosis: Past, Present and Future
DOI:
https://doi.org/10.17140/OOJ-1-e003Keywords:
antiglaucoma, differentiateAbstract
Glaucoma diagnosis is one of the most challenging situation in ophthalmology. In
daily clinical practice, many of glaucoma patients are missed on diagnosis and a lot of those
receiving antiglaucoma therapy may not have the disease. This difficulty may be attributed to
sensitivity and specificity of the diagnostic tools as well as the nature of disease in its early
stages. In the past, subjective clinical evaluation of optic nerve head and Retinal Nerve Fiber
Layer (RNFL) photography enabled diagnosis but with wide variability even among expert observers. Visual field analysis is a major subjective beneficial test, but requires patient cooperation, frequently shows fluctuation. Even tests with reliable indices should be repeated several
times to ensure a reproducible defect.
References
Budenz DL, Michael A, Chang RT, Mcsoley J ,Katz J. Sensitivity and specificity of the stratus OCT for perimetric glaucoma. Ophthalmology. 2005; 112: 3-9. doi: 10.1016/j.ophtha.2004.06.039
Blumberg DM, Dale E, Pensec N, et al. Discrimination of glaucoma patients from healthy individuals using combined parameters from spectral domain optical coherence tomography in an African American population. J glaucoma. 2015. Epub a head of print.
Mokbel T, Elbendary AM, El Sharkawy HT, El Desouky DM. Retinal nerve fiber layer versus optic nerve head evaluation in the diagnosis of glaucoma and glaucoma suspect patients. Journal of Egyptian Ophthalmological Society. 2013; 106: 253-258. doi: 10.4103/2090-0686.131608
Kuang TM, Zhang C, Zangwill LM, Weinreb RN, Medeiros FA. Estimating lead time gained by optical coherence tomogra-phy in detecting glaucoma before development of visual field defects. Ophthalmology. 2015; 122: 2002-2009. doi: 10.1016/j. ophtha.2015.06.015
Hood DC, Raza AS, de Moraes CG, Johnson CA, Liebmann JM, Ritch R. The nature of macular damage in glaucoma as revealed by averaging optical coherence tomography data. Transl Vis Sci Technol. 2012; 1(1): 3. doi: 10.1167/tvst.1.1.3
Wollstein G, Schuman JS, Price LL, et al. Optical coherence tomography (OCT) macular and peripapillary retinal nerve fiber layer measurements and automated visual fields. Am J Ophthalmol. 2004; 138: 218-225. doi: 10.1016/j.ajo.2004.03.019
Tan O, Chopra V, Lu AT, et al. Detection of macular ganglion cell Loss in glaucoma by fourier- domain optical coherence tomog-raphy. Ophthalmology. 2009; 116: 2305-2314. doi: 10.1016/j.ophtha.2009.05.025
Reis AS, Sharpe GP, Yang H, Nicolela MT, Burgoyne CF, Chauhan BC. Optic Disc margin anatomy in glaucoma patients and normal controls with spectral domain optical coherence tomography. Ophthalmology. 2012; 119: 738-747. doi: 10.1016/j.oph-tha.2011.09.054
Kim JH, Lee TY, Lee JW, Lee KW. Comparison of the thickness of the lamina cribrosa and vascular factors in early normal-ten-sion glaucoma with low and high intraocular pressures. Korean J Ophthalmol. 2014; 28: 473-478. doi: 10.3341/kjo.2014.28.6.473
Tatham AJ, Miki A, Weinreb RN, Linda MZ, Medeiros FA. Defects of the lamina cribrosa in eyes with localized retinal nerve fiber layer loss. Ophthalmology. 2014; 121: 110-118. doi: 10.1016/j.ophtha.2013.08.018
Jia Y, Wei E ,Wang X, et al. Optical coherence tomography angiography of optic disc perfusion in glaucoma. Ophthalmology. 2014; 121: 1322-1332. doi: 10.1016/j.ophtha.2014.01.021
Liu L, Jia Y, Takusagawa HL, et al. Optical coherence tomography angiography of the peripapillary retina in glaucoma. JAMA Ophthalmol. 2015; 133: 1045-1052. doi: 10.1001/jamaophthalmol.2015.2225
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