Percutaneous Nephrolithotomy 500 Cases in High-Risk and Altered Renal Function Test: Our Experience at Tertiary Care Centre

Crossmark: check for updates

Authors

  • Shrenik J. Shah
  • Chirag Davara
  • Abhishek Jha
  • Kapil Kachhadiya
  • Rushi Mistry

DOI:

https://doi.org/10.17140/UAOJ-7-144

Keywords:

Percutaneous nephrolithotomy, Stone-free rates, Flexible nephroscope, Staghorn stone

Abstract

Introduction
The study aims to evaluate the results of percutaneous nephrolithotomy (PCNL) in high-risk patients and patients with altered
renal function tests (RFT) and complications in the management of renal stones in our hospital.
Methods
We retrospectively analyzed the outcomes of 500 patients who underwent PCNL between September 2020 and September 2023.
We have analyzed data regarding patient details, investigations, PCNL puncture site, operative duration, number of punctures,
stone-free rates (SFRs), duration of hospital stay, and complications.
Results
Out of 500 patients, 384 (76.87%) were males and 116 (23.13%) were females, with a male-to-female ratio of 3.32:1. The average
age was 40.8±10.4 (mean±SD) (range: 24 to 74-years). The average operative time was 127±37 min (mean±standard deviation
(SD)). The radiation exposure was from 1 min 30 sec to 3 min, with a mean (±SD) of 30 sec. The mean duration of the hospital
stay was 2.7±1.6 days. Complete stone clearance was 87%, whereas SFRs defined by no identifiable stone on a plain radiograph or
ultrasound or residual fragments <5 mm were 90.93%. The complication rate was 2.2%.
Conclusion
The usual course of treatment for renal stones larger than 2 cm is PCNL. Significant factors influencing the stone-free rate include
stone burden, stone type, PCNL puncture, number of punctures, and operative time. With the development of several lithotripsy
procedures and the miniaturization of instruments, PCNL continues to be an excellent therapeutic option for patients with large
renal stones, comorbidities, and changed RFT, with tolerable rates of complications.

References

Pearle MS, Calhoun EA, Curhan GC. Urologic diseases in America project: Urolithiasis. J Urol. 2005; 173(3): 848-857. doi: 10.1097/01.ju.0000152082.14384.d7

Fernstrom I, Johansson B. Percutaneous pyelolithotomy. A new extraction technique. Scand J Urol Nephrol. 1976; 10(3): 257-259. doi: 10.1080/21681805.1976.11882084

Rostami MY, Taghipour-Gorgikolai M, Sharifian R. Treatment of kidney stones using Extracorporeal Shock Wave Lithotripsy (ESWL) and double-J stent in infants. Adv Urol. 2012; 2012: 589038. doi: 10.1155/2012/589038

Lojanapiwat B. The ideal puncture approach for PCNL: Fluoroscopy, ultrasound or endoscopy? Indian J Urol. 2013; 29(3): 208-213. doi: 10.4103/0970-1591.117284

Smith A, Averch TD, Shahrour K, et al. A nephrolithometric nomogram to predict treatment success of percutaneous nephrolithotomy. J Urol. 2013; 190(1): 149-156. doi: 10.1016/j. juro.2013.01.047

Mishra S, Sabnis RB, Desai MR. Percutaneous nephrolithotomy monotherapy for staghorn: Paradigm shift for ‘staghorn morphometry’ based clinical classification. Curr Opin Urol. 2012; 22(2): 148-153. doi: 10.1097/MOU.0b013e32834fc306

Turk C, Knoll T, Petrik A, Sarica K, Skolarikos A, Straub M, Seitz C. Guidelines on urolithiasis. 2010. Website. https://citeseerx.ist. psu.edu/document?repid=rep1&type=pdf&doi=801ad8816594c 100f21fe5287cca0429ec8673dd. Accessed December 6, 2023.

El-Husseiny T, Buchholz N. The role of open stone surgery. Arab J Urol. 2012; 10(3): 284-288. doi: 10.1016/j.aju.2012.03.004

Kumsar S, Aydemir H, Halis F, Kose O, Gokce A, Adsan O. Value of preoperative stone scoring systems in predicting the results of percutaneous nephrolithotomy. Cent European J Urol. 2015; 68(3): 353-357. doi: 10.5173/ceju.2015.552

Chibber PJ. Percutaneous nephrolithotomy for large and staghorn calculi. J Endourol. 1993; 7(4): 293-295. doi: 10.1089/ 10 Shah SJ, et al end.1993.7.293

Fuller A, Razvi H, Denstedt JD, et al. The CROES percutaneous nephrolithotomy global study: The influence of body mass index on outcome. J Urol. 2012; 188(1): 138-144. doi: 10.1016/j. juro.2012.03.013

Kuntz NJ, Neisius A, Astroza GM, et al. Does body mass index impact the outcomes of tubeless percutaneous nephrolithotomy? BJU Int. 2014; 114(3): 404-411. doi: 10.1111/bju.12538

Tomaszewski JJ, Smaldone MC, Schuster T, Jackman SV, Averch TD. Outcomes of percutaneous nephrolithotomy stratified by body mass index. J Endourol. 2010; 24(4): 547-550. doi: 10.1089/ end.2009.0431

Turna B, Umul M, Demiryoguran S, Altay B, Nazli O. How do increasing stone surface area and stone configuration affect overall outcome of percutaneous nephrolithotomy? J Endourol. 2007; 21(1): 34-43. doi: 10.1089/end.2005.0315

Anastasiadis A, Onal B, Modi P, et al. Impact of stone density on outcomes in percutaneous nephrolithotomy (PCNL): An analysis of the clinical research office of the endourological society (CROES) pcnl global study database. Scand J Urol. 2013; 47(6): 509- 514. doi: 10.3109/21681805.2013.803261

Beaghler MA, Poon MW, Dushinski JW, Lingeman JE. Expanding role of flexible nephroscopy in the upper urinary tract. J Endourol. 1999; 13(2): 93-97. doi: 10.1089/end.1999.13.93

Shalaby MM, Abdalla MA, Aboul-Ella HA, El-Haggagy AM, Abd-Elsayed AA. Single puncture percutaneous nephrolithomy for management of complex renal stones. BMC Res Notes. 2009; 2: 62. doi: 10.1186/1756-0500-2-62

Hegarty NJ, Desai MM. Percutaneous nephrolithotomy requiring multiple tracts: Comparison of morbidity with single-tract procedures. J Endourol. 2006; 20(10): 753-760. doi: 10.1089/ end.2006.20.753

Handa RK, Evan AP, Willis LR, et al. Renal functional effects of multiple-tract percutaneous access. J Endourol. 2009; 23(12): 1951-1956. doi: 10.1089/end.2009.0159

Bernardo ON. Percutaneous renal access under fluoroscopic control. In: Smith AD, Badlani GH, Preminger GM, Kavoussi LR, eds. Smith’s Textbook of Endourology. 3rd ed. West Sussex, England: Wiley-Blackwell Publishing Ltd; 2012: 180-188.

Chi T, Masic S, Li J, Usawachintachit M. Ultrasound guidance for renal tract access and dilation reduces radiation exposure during percutaneous nephrolithotomy. Adv Urol. 2016; 2016: 3840697. doi: 10.1155/2016/3840697

Labate G, Modi P, Timoney A, et al. The percutaneous nephrolithotomy global study: Classification of complications. J Endourol. 2011; 25(8): 1275-1280. doi: 10.1089/end.2011.0067 Retrospective Study | Volume 7 | Number 1|

Scholes RL, Browning L, Sztendur EM, Denehy L. Duration of anesthesia, type of surgery, respiratory co-morbidity, predicted VO and smoking predict postoperative pulmonary 2max complications after upper abdominal surgery: An observational study. Aust J Physiotherapy. 2009; 55: 191-198. doi: 10.1016/s0004- 9514(09)70081-9

Akman T, Binbay M, Sari E, et al. Factors affecting bleeding during percutaneous nephrolithotomy: Single surgeon experience. J Endourol. 2011; 25(2): 327-333. doi: 10.1089/end.2010.0302

Cormio L, Preminger G, Saussine C, et al. Nephrostomy in percutaneous nephrolithotomy (PCNL): Does nephrostomy tube size matter? Results from the Global PCNL Study from the Clinical Research Office Endourology Society. World J Urol. 2013; 31(6): 1563-1568. doi: 10.1007/s00345-012-0969-z Submit your article to this journal | https://openventio.org/submit-manuscript/ Retrospective Study | Volume 7 | Number 1| Shah SJ, et al

El-Nahas AR, Shokeir AA. Percutaneous nephrolithotomy: keeping the bridge for one night. Urol Res. 2012; 40(4): 389-393. doi: 10.1007/s00240-011-0432-4

Abdelhafez MF, Wendt-Nordahl G, Kruck S, et al. Minimally invasive versus conventional large-bore percutaneous nephrolithotomy in the treatment of large-sized renal calculi: Surgeon’s preference? Scand J Urol. 2016; 50(3): 212-215. doi: 10.3109/21681805.2016.1155078

Semins MJ, Bartik L, Chew BH, et al. Multicenter analysis of postoperative CT findings after percutaneous nephrolithotomy: Defining complication rates. Urology. 2011; 78(2): 291-294. doi: 10.1016/j.urology.2010.11.008

Downloads

Published

2024-01-10

How to Cite

Shrenik J. Shah, Chirag Davara, Abhishek Jha, Kapil Kachhadiya, & Rushi Mistry. (2024). Percutaneous Nephrolithotomy 500 Cases in High-Risk and Altered Renal Function Test: Our Experience at Tertiary Care Centre. Urology and Andrology , 7(1), 7–11. https://doi.org/10.17140/UAOJ-7-144