Report on a Case of Blighted Ovum

Abstract

Presenting in her late twenties, this case report examines a G6P2 patient at 11-weeks gestation that was diagnosed with a blighted
ovum, as well as the subsequent outcome and methods of additional management. A blighted ovum refers to a fertilized egg that
does not develop, despite the formation of a gestational sac. The most common cause of a blighted ovum is of genetic origin.
Trisomies account for most first trimester miscarriages, while consanguineous marriages result in recurrent miscarriages due to
a blighted ovum. Additionally, a higher percentage of deoxyribonucleic acid (DNA) damage in sperm carries a higher rate of
miscarriage. Nutritional factors that may lead to a blighted ovum include low-levels of copper, prostaglandin E2, and anti-oxidative
enzymes. High body mass index (BMI), especially in women with a BMI≥30 kg/m2
has been shown to be linked to a blighted
ovum. Globally, it has been shown that a blighted ovum is a serious adverse event related to vaccination against dengue fever