Knowledge of the Molecular Signaling Pathways Improves the Chances of Treatment of Gastrointestinal Stromal Tumors

Authors

  • Joana Espiga de Macedo

Abstract

Gastrointestinal Stromal Tumors (GISTs) are the most common mesenchymal (nonepithelial) tumors of the gastrointestinal tract. A better molecular understanding of this entity, as Christopher L. Cordless in Modern Pathology in 20141 demonstrated, GISTs mainly a result from two-level changes in two Oncogenes: KIT oncogene (75%) and PDGFRA oncogene (α receptor platelet-derived growth factor) which occurs in about 10% of cases; the remaining 15% are designated wild type tumors.

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Published

2015-08-05

How to Cite

Joana Espiga de Macedo. (2015). Knowledge of the Molecular Signaling Pathways Improves the Chances of Treatment of Gastrointestinal Stromal Tumors. Cancer Studies and Molecular Medicine , 2(1), 69–71. Retrieved from https://openventio.us/index.php/CSMM/article/view/1410

Issue

Vol. 2 No. 1 (2015): Volume 2 Issue 1 2015

Section

Articles

License

All content published in Cancer Studies and Molecular Medicine (CSMM) is licensed under the Creative Commons Attribution 4.0 International License (CC BY 4.0). This license allows anyone to copy, distribute, transmit, and adapt the work — including for commercial purposes — provided appropriate credit is given to the original author(s) and source.