Gouty Tophi: Two Case Report

Authors

  • Rosa Giménez-García Department of Dermatology, Hospital Universitario Río Hortega, Valladolid, Spain
  • Gonzalo Cabezón-Villalba Department of Dermatology, Hospital Universitario Río Hortega, Valladolid, Spain
  • Laura Perez-Gimenez Department of Dermatology, Hospital Universitario Río Hortega, Valladolid, Spain
  • María Jesús Gimenez-Mazuelas Department of Dermatology, Hospital Universitario Río Hortega, Valladolid, Spain

DOI:

https://doi.org/10.17140/DRMTOJ-2-122

Abstract

Gouty tophi represent a symptom of chronic form of gout resulting from accumulation of
monosodium urate crystals in tissues, which is the most prevalent form of inflammatory arthritis.
The tophus represents a granulomatous inflammatory response to monosodium urate crystals.
1,2 Women are less likely to have gout than men but they develop it in the postmenopausal
years and have comorbidities such renal disease, diabetes or concomitant use of diuretics more
common as compared with men.3 We present two cases of gouty tophi.

References

Thissen CA, Frank J, Lucker GP. Tophi as first clinical sign of gout. Int J Dermatol. 2008; 47(Suppl 1): 49-51. doi: 10.1111/j.1365-4632.2008.03961.x

Chhana A, Dalbeth N. The gouty tophus: A review. Curr Rheumatol Rep. 2015; 17: 19. doi: 10.1007/s11926-014-0492-x

Harrold LR, Etzel CJ, Gibofsky A, et al. Sex differences in gout characteristics: Tailoring care for women and men. BMC Musculoskelet Disord. 2017. 14; 18: 108. doi: 10.1186/s12891- 017-1465-9

Cottrell E, Crabtree V, Edwards J, Roddy E. Improvement in the management of gout is vital and overdue: An audit from a UK primary care medical practice. BMC Family Practice. 2013; 14: 170-180. doi: 10.1186/1471-2296-14-170

Schlee S, Bollheimer LC, Bertsch T, Sieber CC, Härle P. Crystal arthritides - gout and calcium pyrophosphate arthritis: Part 2: Clinical features, diagnosis and differential diagnostics. Z Gerontol Geriatr. 2017; doi: 10.1007/s00391-017-1198-2

Ting K, Graf SW, Whittle SL. Update on the diagnosis and management of gout. Med J Aust. 2015; 203: 86-88. doi: 10.5694/mja14.00953

Hainer B, Matheson E, Wilkes T. Diagnosis, treatment and prevention of gout. Am Fam Physician. 2014; 90(12): 831- 836. Web site. http://www.aafp.org/afp/2014/1215/p831.html. Accessed March 22, 2017

Abhishek A, Roddy E, Doherty M. Gout - A guide for the general and acute physicians. Clin Med (Lond). 2017; 17: 54-59. doi: 10.7861/clinmedicine.17-1-54

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Published

2017-04-06

How to Cite

Rosa Giménez-García, Gonzalo Cabezón-Villalba, Laura Perez-Gimenez, & María Jesús Gimenez-Mazuelas. (2017). Gouty Tophi: Two Case Report. Dermatology, 2(1), 16–17. https://doi.org/10.17140/DRMTOJ-2-122

Issue

Vol. 2 No. 1 (2017): Volume 2 Issue 1 2017

Section

Articles

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