Vertebral Artery Dissection Mimicking Migraine: A Case Report

Authors

  • Rahalkar Kshitij (Ed), FAMS, GDOM Department of Emergency Medicine, Singapore General Hospital, Outram Road 169608, Singapore
  • Hong K. Lau (Ed), FAMS, GDOM Department of Emergency Medicine, Singapore General Hospital, Outram Road 169608, Singapore
  • R Ponampalam (Ed), FAMS, GDOM Department of Emergency Medicine, Singapore General Hospital, Outram Road 169608, Singapore

DOI:

https://doi.org/10.17140/EMOJ-7-162

Keywords:

Vertebral artery dissection, Migraine, Headache, Neck pain

Abstract

Vertebral artery dissection (VAD) is caused by an intimal tear that leads to bleeding into the vascular wall, which may cause vascular occlusion by thrombus formation and subsequent distal emboli (leading to ischemic stroke), aneurysm formation and sub arachnoid hemorrhage. Cervical artery dissections (either carotid or vertebral artery dissection) are an important cause of stroke in patients under 50-years of age. Headache with or without neck pain is a common symptom. Usually, it occurs with focal neuro logical signs but sometimes it may occur without any neurological deficits and may mimic migraine. Often it occurs spontaneously without trauma but sometimes there is history of minor traumas, sudden neck movements or chiropractic manipulation. Imaging modalities include magnetic resonance imaging (MRI) brain, magnetic resonance angiography (MRA), and computed tomography angiography (CTA). Treatment involves anticoagulation or antiplatelet agents.

References

Debette S, Grond-Ginsbach C, Bodenant M, Kloss M, Engelter S, Metso T, et al. Differential features of carotid and vertebral ar-tery dissections: The CADISP study. Neurology. 2011; 77(12): 1174- 1181. doi: 10.1212/WNL.0b013e31822f03fc

Hinse P, Thie A, Lachenmayer L. Dissection of the extracra-nial vertebral artery: Report of four cases and review of the litera-ture. J Neurol Neurosurg Psychiatry. 1991; 54: 863-869. doi: 10.1136/ jnnp.54.10.863

Engelter ST, Grond-Ginsbach C, Metso TM, Metso AJ, Kloss M, Debette S, et al. Cervical artery dissection: Trauma and other potential mechanical trigger events. Neurology. 2013; 80(21): 1950- 1957. doi: 10.1212/WNL.0b013e318293e2eb

Fukuhara K, Ogata T, Ouma S, Tsugawa J, Matsumoto J, Abe H, Higashi T, Inoue T, Tsuboi Y. Impact of initial symptom for accurate diagnosis of vertebral artery dissection. Int J Stroke. 2015; 10 Suppl A100: 30-33. doi: 10.1111/ijs.12546

Arnold M, Cumurciuc R, Stapf C, Favrole P, Berthet K, Bouss-er M-G. Pain as the only symptom of cervical artery dissection. J Neurol Neurosurg Psychiatry. 2006; 77: 1021-1024. doi: 10.1136/ jnnp.2006.094359 Case Report | Volume 7 | Number 1 | Kshitij R et al

Silbert PL, Mokri B, Schievink WI. Headache and neck pain in spontaneous internal carotid and vertebral artery dissections. Neu-rology. 1995; 45(8): 1517-1522. doi: 10.1212/wnl.45.8.1517

Arnold M, Kappeler L, Georgiadis D, Berthet K, Keserue B, Bousser MG, Baumgartner RW. Gender differences in spontane-ous cervical artery dissection. Neurology. 2006; 67(6): 1050-1052. doi: 10.1212/01.wnl.0000237341.30854.6a

Headache Classification Committee of the International Head-ache Society (IHS). The international classification of head-ache disorders, 3rd edition. Cephalalgia. 2018; 38(1): 1-211. doi: 10.1177/0333102417738202

Teodoro T, Ferreira J, Franco A, Almeida V, Casimiro C, Coelho M, et al. Vertebral artery dissection mimicking status migraino-sus. Am J Emerg Med. 2013; 31(12): 1721.e3-e5. doi: 10.1016/j. ajem.2013.07.025

Donnelly A, Sinnott B, Boyle R, Rennie I. Beware the middle-aged migraine: Internal carotid artery dissection mimicking mi-graine in the emergency department. BMJ Case Reports. 2017; 2017: bcr-2017-221774. doi: 10.1136/bcr-2017-221774

Jatuzis D, Valaikiene J. Migraine-like presentation of vertebral artery dissection after cervical manipulative therapy. Perspectives in Medicine. 2012; 1(1-12): 452-454. doi: 10.1016/j.permed.2012.03.010

Morelli N, Mancuso M, Gori S, Maluccio MR, Cafforio G, Chiti A, et al. Vertebral artery dissection onset mimics migraine with aura in a graphic designer. Headache. 2008; 48(4): 621-624. doi: 10.1111/j.1526-4610.2008.01066.x

Sakakibara S, Nakatani T, Yamamoto H, Motooka A, Hashi-moto T, Saito Y. A case of severe headache attributed to vertebral artery dissection. JA Clin Rep. 2019; 5: 27. doi: 10.1186/s40981- 019-0247-9

De Giuli V, Grassi M, Lodigiani C, Patella R, Zedde M, Gan-dolfo C, et al. Italian project on stroke in young adults investiga-tors. association between migraine and cervical artery dissection: The italian project on stroke in young adults. JAMA Neurol. 2017; 74(5): 512-518. doi: 10.1001/jamaneurol.2016.5704

Brandt T, Morcher M, Hausser I. Association of cervical artery dissection with connective tissue abnormalities in skin and arter-ies. Front Neurol Neurosci. 2005; 20: 16-29. doi: 10.1159/000088131

Vertinsky AT, Schwartz NE, Fischbein NJ, Rosenberg J, Albers GW, Zaharchuk G. Comparison of multidetector CT angiography and MR imaging of cervical artery dissection. AJNR Am J Neuro-radiol. 2008; 29(9): 1753-1760. doi: 10.3174/ajnr.A1189

Engelter ST, Rutgers MP, Hatz F, Georgiadis D, Fluri F, Sekoranja L, et al. Intravenous thrombolysis in stroke attributable to cervical artery dissection. Stroke. 2009; 40(12): 3772-3776. doi: 10.1161/STROKEAHA.109.555953

Zinkstok SM, Vergouwen MD, Engelter ST, Lyrer PA, Bonati LH, Arnold M, et al. Safety and functional outcome of throm-bolysis in dissection-related ischemic stroke: A meta-analysis of individual patient data. Stroke. 2011; 42: 2515-2520. doi: 10.1161/ STROKEAHA.111.617282

Kasner SE. CADISS: A feasibility trial that answered its ques-tion. Lancet Neurol. 2015; 14(4): 342-343. doi: 10.1016/S1474- Submit your article to this journal | https://openventio.org/submit-manuscript/ 24 Kshitij R et al 4422(14)70271-6

Engelter ST, Traenka C, Gensicke H, Schaedelin SA, Luft AR, Simonetti BG, et al. Aspirin versus anticoagulation in cervical ar-tery dissection (TREAT-CAD): An open-label, randomised, non-inferiority trial. Lancet Neurol. 2021; 20: 341-350. doi: 10.1016/ S1474-4422(21)00044-2 Case Report | Volume 7 | Number 1 |

Downloads

Published

2021-09-27

How to Cite

Rahalkar Kshitij, Hong K. Lau, & R Ponampalam. (2021). Vertebral Artery Dissection Mimicking Migraine: A Case Report. Emergency Medicine, 7(1), 21–24. https://doi.org/10.17140/EMOJ-7-162