Halting Coronavirus Replication

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Authors

  • Kira Smith Department Clinical and Experimental Medicine, Novara (NO), Italy

DOI:

https://doi.org/10.17140/EPOJ-5-119

Keywords:

COVID-19, Coronavirus replication, SIRT1 inhibitors, p53, Tenovin

Abstract

Sirtuin 1 (SIRT1) inhibitors can reduce replication of many viruses with certain characteristics similar to those of coronaviruses, while the p53 protein is another important factor in the down-regulation of viral growth. Tenovin is a class of small molecules that inhibit Sirtuin 1 and 2, in addition to activating the p53 protein, by means of regulating the interactions used by coronaviruses as a self-defense mechanism. By blocking virus growth and continuous replication, with already tested antiviral medicines, the promise of coronavirus disease 2019 (COVID-19) eradication exists.

References

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Published

2020-10-05

How to Cite

Kira Smith. (2020). Halting Coronavirus Replication. Epidemiology, 5(1), 13–15. https://doi.org/10.17140/EPOJ-5-119

Issue

Vol. 5 No. 1 (2020): Volume 5 Issue 1 2020

Section

Articles

License

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

All content published in Epidemiology (EOJ) is licensed under the Creative Commons Attribution 4.0 International License (CC BY 4.0). This license allows anyone to copy, distribute, transmit, and adapt the work — including for commercial purposes — provided appropriate credit is given to the original author(s) and source.