The Importance of Enzyme Substitution Therapy in Early Pancreas Exocrines of Insufficiency
DOI:
https://doi.org/10.17140/GOJ-4-131Keywords:
Chronic pancreatic insufficiency, Enzyme, Body mass index (BMI), Digestive tractAbstract
Introduction
Functional disorders of the digestive tract are a common occurrence in the doctor’s office. In addition to functional dyspepsia, 35% of dyspepsia are unresolved dyspepsia, which are a symptom of the early stage of pancreatic exocrine insufficiency.
Aim
Based on clinical experience, we can suspect and detect chronic pancreatic insufficiency at an early stage, which is the aim of this paper.
Method
To demonstrate the efficacy of enzyme replacement therapy in the early stage of pancreatic exocrine insufficiency using the case report of the patient.
Results
Results confirms significance and effectiveness of creon as an enzyme replacement therapy in the treatment of malabsorption and maldigestion.
Conclusion
Creon (pancreatin) showed great effect in the treatment of dyspepsia and anorexia nervosa, body mass index (BMI) for 30 days increased from 15.9 to 17.4, which leads us to the conclusion that unrecognized chronic pancreatic insufficiency can be expected in long-term dyspepsia.
References
Summary of Product Characteristics. Creon® 25000. Data Health. Web site. https://data.health.gov.il/drugs/alonim/Cre-on_25000_dr__Pancreatin_300mg_1437031539160.pdf. Accessed November 2, 2019.
Demir K. Pancreatic dyspepsia: A place for pancreatic insuf-ficiency in dyspepsia. Eur J Surg Sci. 2012; 3(1): 1-4.
Löhr JM, Hummel FM, Pirilis KT, Steinkamp G, Körner A, Henniges F. Properties of different pancreatin preparations used in pancreatic exocrine insufficiency. Eur J Gastroenterol Hepatol. 2009; 21(9): 1024-1031. doi: 10.1097/MEG.0b013e328328f414
Zigic D, Janosevic-Dotlic S, Ivankovic D, Pertot V, Konstanti-novic D. Methodology of Scientific Research. Belgrade, Serbia: Depart-ment of General Medicine SLD, Department of General Medi-cine, Faculty of Medicine; 1992. Case Report | Volume 4 | Number 1|
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