Why Novel Nanoparticle-based Delivery Platforms Hold Key for HIV/AIDS Treatment and Prevention?

Abstract

The administration of highly active antiretroviral therapy (HAART) to HIV/AIDS patients has greatly reduced their morbidity and mortality. However, HAART regimens have myriad of limitations, which make it difficult to completely eradicate HIV/AIDS from the body. Cells harboring latent HIV reside in restricted areas in the body: cellular and anatomical reservoirs. The residing of HIV in these restricted sanctuaries makes HAART regimens incapable of completely eliminating HIV from the body.