Lipocalin-2 in Stroke

Authors

  • Wen-Hai Chou
  • Yi-Chinn Weng
  • Varun Kumar

Keywords:

Lipocalin-2; NGAL; 24p3; Stroke; Reperfusion injury; Neutrophil; PKC; Phosphorylation; Biomarker.

Abstract

Stroke is a leading cause of adult disability in the United States. However, limited
number of molecularly targeted therapy exists for stroke. Recent studies have shown that Lipocalin-2 (LCN2) is an acute phase protein mediating neuroinflammation after ischemic and
hemorrhagic strokes. This review is an attempt to summarize some LCN2-related research findings and discuss its role in stroke.

Downloads

Published

2015-04-17

Issue

Volume 2 Issue 1 2015

Section

Articles