Lipocalin-2 in Stroke
DOI:
https://doi.org/10.17140/NOJ-2-109Keywords:
Lipocalin-2; NGAL; 24p3; Stroke; Reperfusion injury; Neutrophil; PKC; Phosphorylation; Biomarker.Abstract
Stroke is a leading cause of adult disability in the United States. However, limited
number of molecularly targeted therapy exists for stroke. Recent studies have shown that Lipocalin-2 (LCN2) is an acute phase protein mediating neuroinflammation after ischemic and
hemorrhagic strokes. This review is an attempt to summarize some LCN2-related research findings and discuss its role in stroke.
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