Comments on Acute Pancreatitis’ Progression Hypotheses to Chronic Pancreatitis
DOI:
https://doi.org/10.17140/poj-7-e015Keywords:
controversies, morphologicalAbstract
From our experience and several research studies, acute pancre
atitis (AP) progression to chronic pancreatitis (CP) is a com
plex issue in the medical field. The progression was hypothesized
many years ago but still, many controversies are not clarified in the
present literature.
CP is a well-known invaliding disease that causes a sensi
tive decrease in life expectancy. This pathology is associated with
several genetic alterations that can provoke morphological abnor
malities.1
On the other hand, AP is a syndrome (and it must be
considered more a systemic than confined pathology) caused by
the release of pancreatic enzymes into the bloodstream and sub
sequent activation of systemic inflammatory systems (as comple
ments).2
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