Should We Be Concerned About Intraductal Papillary Mucinous Neoplasm's Unsettling Features?
Keywords:
Worrisome features, High-risk stigmata, Intraductal papillary mucinous neoplasm (IPMN), Pancreatic neoplasm, Pancreatic high-grade dysplasia, Pancreatic low-grade dysplasiaAbstract
Although worrisome features represent an indication to perform endoscopic ultrasound study, recent studies have showed that these conditions are not strictly related to high risk of malignancy. Pancreatic resection for worrisome imaging features often demonstrates pathology consistent with low-grade dysplasia. Worrisome features should be considered as indicators of mostly low-grade dysplasia. High-risk stigmata are more consistent for diagnosis of malignant lesions.
References
Dbouk M, Brewer Gutierrez OI, Lennon AM, et al. Guidelines on management of pancreatic cysts detected in high-risk indivi-duals: An evaluation of the 2017 Fukuoka guidelines and the 2020 International Cancer of the Pancreas Screening (CAPS) consor-tium statements. Pancreatology. 2021; 21(3): 613-621. doi: 10.1016/j. pan.2021.01.017
Izumo W, Higuchi R, Furukawa T, et al. Importance of each high-risk stigmata and worrisome features as a predictor of high-grade dysplasia in intraductal papillary mucinous neoplasms of the pancreas. Pancreatology. 2020; 20(5): 895-901. doi: 10.1016/j. pan.2020.06.011 Submit your article to this journal | https://openventio.org/submit-manuscript/ e2 Dioscoridi L PUBLISHERS Results
Li B, Guo SW, Shi XH, et al. Diagnostic efficacy for predicting intraductal papillary mucinous neoplasms of the pancreas with high grade dysplasia or invasive carcinoma based on the surgery indications in different guidelines. Zhonghua Wai Ke Za Zhi. 2021; 59(5): 359-365. doi: 10.3760/cma.j.cn112139-20200507-00365
Wilson GC, Maithel SK, Bentrem D, et al. Are the current gui-delines for the surgical management of intraductal papillary mu-cinous neoplasms of the pancreas adequate? A multi-institutional study. J Am Coll Surg. 2017; 224(4): 461-469. doi: 10.1016/j.jam-collsurg.2016.12.031
Sugimoto M, Elliott IA, Nguyen AH, et al. Assessment of a revised management strategy for patients with intraductal papillary mucinous neoplasms involving the main pancreatic duct. JAMA Surg. 2017; 152: e163349. doi: 10.1001/jamasurg.2016.3349
Shimizu Y, Kanemitsu Y, Sano T, et al. A nomogram for pre-dicting the probability of carcinoma in patients with intraductal papillary-mucinous neoplasm. World J Surg. 2010; 34: 2932-2938. doi: 10.1007/s00268-010-0785-9
Downloads
Published
How to Cite
Issue
Section
License

This work is licensed under a Creative Commons Attribution 4.0 International License.
All content published in Pancreas (POJ) is licensed under the Creative Commons Attribution 4.0 International License (CC BY 4.0). This license allows anyone to copy, distribute, transmit, and adapt the work — including for commercial purposes — provided appropriate credit is given to the original author(s) and source.