MRI Investigation of Optic Radiations in Human Brain: New Findings and Technical Considerations

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Authors

  • Alessandro Arrigo Department of Biomedical Sciences and Morphological and Functional Images, University of Messina, Messina, Italy
  • Alessandro Calamuneri Department of Biomedical Sciences and Morphological and Functional Images, University of Messina, Messina, Italy
  • Enricomaria Mormina Department of Biomedical Sciences and Morphological and Functional Images, University of Messina, Messina, Italy

DOI:

https://doi.org/10.17140/ROJ-1-e002

Keywords:

Optic radiations; Tractography; Diffusion MRI; DTI; CSD.

Abstract

Optic Radiations (ORs) are two white matter fiber bundles allowing direct connection between homolateral Lateral Geniculate Nucleus (LGN) and visual cortex. From the anatomical point of view, ORs are conventionally divided in three different portions, namely anterior, middle and posterior; the Meyer’s loop represents the anterior portion, and it has been shown to be a bundle with a very high variability in human brain.1-3 The latter aspect has to be taken into account when studying ORs in clinical and surgical contexts. Indeed, ORs represent eloquent white matter bundles often reconstructed by means of Magnetic Resonance Imaging (MRI) based approaches in order to assess their involvement by pathological conditions as well as to prevent post-surgical damages. Both these conditions can compromise visual function by causing, for instance, visual field deficits. 

 

References

Párraga RG, Ribas GC, Welling LC, et al. Microsurgical anatomyof the optic radiation and related fibers in 3-dimensional images. Neurosurgery. 2012; 71(Suppl 1): 160-171. doi: 10.1227/NEU.0b013e3182556fde

Pujari VB, Jimbo H, Dange N, et al. Fiber dissection of the visualpathways: analysis of the relationship of optic radiations to lateral ventricle: a cadaveric study. Neurol India. 2008; 56(2): 133-137. doi: 10.4103/0028-3886.41989

Nilsson D, Starck G, Ljungberg M, et al. Intersubjectvariability in the anterior extent of the optic radiation assessed by tractogra-phy. Epilepsy Res. 2007; 77(1): 11-16. doi: 10.1016/j.eplepsyres.2007.07.012

Longo D, Fauci A, Kasper D, et al. Harrison’s Principles of Internal Medicine. 18th ed. McGraw-Hill Professional, 2011: 1 and 2.

Greenberg D, Aminoff M, Simon R. Clinical Neurology 8/E. McGraw-Hill Professional, 2012.

Baldwin MK, Kaskan PM, Zhang B, et al. Cortical and subcortical connections of V1 and V2 in early postnatal macaque mon-keys. J Comp Neurol. 2012; 520(3): 544-569. doi: 10.1002/cne.22732

Alvarez I, Schwarzkopf DS, Clark CA. Extrastriate projections in human opticradiation revealed by fMRI-informed tractography. Brain Struct Funct. 2015; 220(5): 2519-2532. doi: 10.1007/s00429-014-0799-4

Arrigo A, Calamuneri A, Mormina EM, et al. New Insights in the optic radiations connectivity in the human brain. Invest Oph-thalmol Vis Sci. 2016; 57(1): 1-5. doi: 10.1167/iovs.15-18082

Bridge H, Thomas O, Jbabdi S, Cowey A. Changes inconnectivity after visual cortical brain damage underlie alteredvisual func-tion. Brain. 2008; 131: 1433-1444. doi: 10.1093/brain/awn063

Schmid MC, Mrowka SW, Turchi J, et al. Blindsight depends on the lateral geniculate nucleus. Nature. 2010; 466(7304): 373- 377. doi: 10.1038/nature09179

Bridge H, Hicks SL, Xie J, et al. Visual activation of extra-striatecortex in the absence of V1 activation. Neuropsychologia. 2010; 48: 4148-4154. doi: 10.1016/j.neuropsychologia.2010.10.022

Jones DK, Cercignani M. Twenty-five pitfalls in the analysis ofdiffusion MRI data. NMR Biomed. 2010; 23(7): 803-820. doi: 10.1002/nbm.1543

Farquharson S, Tournier JD, Calamante F, Fabinyi G, et al. White matter fiber tractography: whywe need to move beyond DTI. J Neurosurg. 2013; 118(6): 1367-1377. doi: 10.3171/2013.2.JNS121294

Kier EL, Staib LH, Davis LM, Bronen RA. MR imaging of thetemporal stem: anatomic dissection tractography of the unci-natefasciculus, inferior occipitofrontal fasciculus, and Meyer’s loop of theoptic radiation. AJNR Am J Neuroradiol. 2004; 25(5): 677-691.

Peltier J, Verclytte S, Delmaire C, et al. Microsurgical anatomy of the temporal stem: clinical relevance and correlations with diffusion tensor imaging fiber tracking. J Neurosurg. 2010; 112(5): 1033-1038. doi: 10.3171/2009.6.JNS08132

Rabbo AF, Koch G, Lefevre C, Seizeur R. Direct geniculo-extrastriate pathways: a review of the literature. Surg Radiol Anat. 2015; 37: 891-899. doi: 10.1007/s00276-015-1450-7

Tournier JD, Calamante F, Connelly A. Robust determination of the fibre orientation distribution in diffusion MRI: nonnegativ-ity constrained super-resolved spherical deconvolution. Neuroimage. 2007; 35: 1459-1472. doi: 10.1016/j.neuroimage.2007.02.016

Tournier JD, Yeh CH, Calamante F, et al. Resolving crossing fibres using constrained spherical deconvolution: validation using diffusion weighted imaging phantom data. Neuroimage. 2008; 42: 617-625. doi: 10.1016/j.neuroimage.2008.05.002

Jeurissen B, Leemans A, Tournier JD, et al. Investigating the prevalence of complex fiber configurationsin white matter tissue with diffusion magnetic resonance imaging. Hum Brain Mapp. 2013; 34: 2747-2766. doi: 10.1002/hbm.22099

Lim JC, Phal PM, Desmond PM, et al. Probabilistic MRI tractography of the optic radiation using constrained spherical decon-volution: a feasibility study. PLoS One. 2015; 10(3): e0118948. doi: 10.1371/journal.pone.0118948

Martínez-Heras E, Varriano F, Prčkovska V, et al. Improved framework for tractography reconstruction of the optic radiation. PLoS One. 2015; 10(9): e0137064. doi: 10.1371/journal.pone.0137064

Ferrera VP, Nealey TA, Maunsell JH. Responses in macaquevisual area V4 following inactivation of the parvocellular and mag-nocellular LGN pathways. J Neurosci. 1994; 14(4): 2080-2088.

Ungerleider LG, Galkin TW, Desimone R, Gattass R. Cortical connections of area V4 in the macaque. Cereb Cortex. 2008; 18: 477-499. doi: 10.1093/cercor/bhm061

Duncan JS. Imaging in the surgical treatment of epilepsy. Nat Rev Neurol. 2010; 6: 537-550. doi: 10.1038/nrneurol.2010.131

Winston GP, Daga P, Stretton J, et al. Optic radiation tractography and vision inanterior temporal lobe resection. Ann Neurol. 2012; 71(3): 334-341. doi: 10.1002/ana.22619

Piper RJ, Yoong MM, Kandasamy J, Chin RF. Application of diffusion tensor imaging and tractography of the optic radiation inanterior temporal lobe resection for epilepsy: a systematic review. Clin Neurol Neurosurg. 2014; 124C: 59-65. doi: 10.1016/j. clineuro.2014.06.013

Cho JM, Kim EH, Kim J, et al. Clinical use of diffusion tensor image-merged functional neuronavigationfor brain tumor sur-geries: review of preoperative, intraoperative, andpostoperative data for 123 cases. Yonsei Med J. 2014; 55(5): 1303-1309. doi: 10.3349/ymj.2014.55.5.1303

Mormina E, Longo M, Arrigo A, et al. MRI tractography of corticospinal tract and arcuate fasciculus in high-grade gliomas performed by constrained spherical deconvolution: qualitative and quantitative analysis. AJNR Am J Neuroradiol. 2015; 36(10): 1853-1858. doi: 10.3174/ajnr.A4368

Arrigo A, Mormina E, Calamuneri A. The pre-surgical planning of brainneoplasms: from diffusion tensor imaging to more ad-vanced approaches. Radiol Open Journal. 2015; 1(1): e1-e5.

Jellison BJ, Field AS, Medow J, et al. Diffusion tensor imaging of cerebral white matter: a pictorialreview of physics, fiber tract anatomy, and tumor imaging patterns. AJNR Am J Neuroradiol. 2004; 25(3): 356-369.

Dai H, Mu KT, Qi JP, et al. Assessment of lateral geniculate nucleus atrophywith 3T MR imaging and correlation with clinical stage of glaucoma. AJNR Am J Neuroradiol. 2011; 32(7): 1347-1353. doi: 10.3174/ajnr.A2486

El-Rafei A, Engelhorn T, Wärntges S, et al. Glaucoma classification based on histogram analysis of diffusion tensor imaging measures in the optic radiation. ComputerAnalysis of Images and Patterns Lecture Notes in Computer Science. 2011; 6854: 529-536.

Liu Y, Duan Y, He Y, et al. A tract-based diffusion study of cerebral white matter inneuromyelitis optica reveals widespread pathological alterations. Mult Scler. 2012; 18(7): 1013-1021. doi: 10.1177/1352458511431731

Published

2016-01-25

How to Cite

Alessandro Arrigo, Alessandro Calamuneri, & Enricomaria Mormina. (2016). MRI Investigation of Optic Radiations in Human Brain: New Findings and Technical Considerations. Radiology, 1(1), e6-e10. https://doi.org/10.17140/ROJ-1-e002