Stereotactic Body Radiation Therapy Treatment for Prostate Cancer: From Setup to Delivery Strategies

Abstract

Stereotactic Body Radiation Therapy (SBRT) of prostate cancer has garnered increasing attention
owing to its proposed low a/b value, which is close to 1.5 Gy.1 Recent clinical data support
the low value for a/b ratio as predicted by radiobiological models; hence, large doses per fraction
should result in a higher probability of tumor control together with a reduced probability
of complications for healthy tissue. In this paper, we focused on the technical parameters and
treatment strategies adopted in the hypofractionation (HF) studies published in literature.