Mind the Gap Between the Bench and the Bed: The General Anesthetics-Induced Neurotoxicity in the Real World

Authors

  • Jieshu Zhou Training Anaesthetist, Department of Anesthesiology and Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, West China Second University Hospital, Sichuan University, Chengdu Shi, Sichuan Sheng, China
  • Han Huang Training Anaesthetist, Department of Anesthesiology and Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, West China Second University Hospital, Sichuan University, Chengdu Shi, Sichuan Sheng, China; Translational Neuroscience Centre, West China Hospital, Sichuan University, Chengdu Shi, Sichuan Sheng, China

DOI:

https://doi.org/10.17140/RPAOJ-2-115

Abstract

From the very beginning of Morton’s successful demonstration of surgical anesthesia, reversibility has been identified as one of the unique characteristics of anesthesia. However, recent studies just reveal the opposite; general anesthetics (GAs) produce long-term, if not permanent, effects in the human brain, especially in the immature brain, at clinically relevant concentrations for clinical relevant durations, so-called the neurotoxicity of GAs on immature brains.

References

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Published

2017-12-27

How to Cite

Jieshu Zhou, & Han Huang. (2017). Mind the Gap Between the Bench and the Bed: The General Anesthetics-Induced Neurotoxicity in the Real World. Research and Practice in Anesthesiology, 2(2), 40–41. https://doi.org/10.17140/RPAOJ-2-115

Issue

Vol. 2 No. 2 (2017): Volume 2 Issue 2 2017

Section

Articles

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All content published in Research and Practice in Anesthesiology (RPA) is licensed under the Creative Commons Attribution 4.0 International License (CC BY 4.0). This license allows anyone to copy, distribute, transmit, and adapt the work — including for commercial purposes — provided appropriate credit is given to the original author(s) and source.