Facial Rejuvenation and Patients Satisfaction with the Fourth Generation of Aptos P(LA/CL)–Hyaluronic Acid Threads: A 12-Month Study

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Authors

  • Albina Kajaia Clinic of Plastic and Aesthetic Surgery and Cosmetology,Total Charm Vake, 87B Z. Paliashvili,Tbilisi 0162, Georgia

DOI:

https://doi.org/10.17140/tcoj-6-120

Keywords:

Facelift, Midface lifting, Aptos threads, P(LA/CL)-HA threads, NAMICA technology, Face rejuvenation

Abstract

Objective
New generation of biodegradable thread: polycaprolactone (P(LA/CL) copolymer monofilament thread coated by the shell composed of nano- and microparticles of hyaluronic acid (HA) encapsulated into polycaprolactone (P(LA/CL) copolymer shell has been lately introduced by Aptos company as the NAnoMIcroCApsules (NAMICA) technology. NAMICA, which utilizes particles consisting of unstabilized (non-cross-linked) HA surrounded by P(LA/CL) nanofibers, securely fixed to lifting threads, is thought to provide long-lasting biostimulating and rejuvenation effects. This study evaluates the 12 month-long skin quality improvement, and lifting effects of the P(LA/CL)-HA threads produced with NAMICA technology on the middle and lower third of the face.
Research Design and Methods
Twenty-six (26) patients, women and men aged 30 to 65-years underwent a mid and lower face lifting using the 4th generation of Aptos P(LA/CL)-HA threads created with NAMICA technology. The threads were applied on the right and left sides symmetrically per 5 threads on each side of the face. Patients’ satisfaction and facelift were assessed at study follow-ups.
Main Outcome Measures
Skin quality improvement, midface lift, and patients’ satisfaction with the procedure outcome overall, and specifically, satisfaction with facial appearance, skin, cheekbones and cheeks, lower face, and jawline were explored at 4, 9 and 12 months after the procedure and compared with the scores given at the enrolment.
Results
Our results demonstrate that the NAMICA technology provides a significant skin quality improvement, and facial lift which is preserved for 12 months from treatment. The skin quality parameters as wrinkles, evenness and redness improvement were observed during 12 months after new generation threads implantation. The procedure is well-tolerated in all studied subjects with no adverse effects or undesirable symptoms at later follow-ups. Patients’ satisfaction scores are kept significantly high for all measured parameters.
Conclusion
This study supports the use of 4th generation of P(LA/CL)-HA threads with NAMICA technology to achieve and preserve an improvement in skin quality, meaningful facial lift, and patients’ satisfaction for at least 12©months post-treatment.

References

Sulamanidze M, Sulamanidze G, Sulamanidze C. Elimination of aesthetic deformations of the midface area, our experience. Aesthetic Plast Surg. 2018; 42(3): 774-790. doi: 10.1007/s00266-018- 1112-3

Rezaee Khiabanloo S, Jebreili R, Aalipour E, Saljoughi N, Shahi-di A. Outcomes in thread lift for face and neck: A study performed with silhouette soft and promo happy lift double needle, innovative and classic techniques. J Cosmet Dermatol. 2019; 18(1): 84-93. doi: 10.1111/jocd.12745

Ilankovan V. Erratum to: recent advances in face lift to achieve facial balance. J Maxillofac Oral Surg. 2017; 16(1): 134. doi: 10.1007/ s12663-017-0999-6

Aitzetmueller MM, Centeno Cerdas C, Nessbach P, et al. Polydioxanone threads for facial rejuvenation: Analysis of qual-ity variation in the market. Plast Reconstr Surg. 2019; 144(6): 1002e-1009e. doi: 10.1097/PRS.0000000000006289

Sulamanidze GM, Sulamanidze MA, Sulamanidze KM, Kajaia AA, Giorgadze SG. The subcutaneous tissue reaction on poly (L-lactide-co-caprolactone) based threads. Int J Clin Exp Dermatol. 2018; 3(2): 1-9. doi: 10.33140/ijced.03.02.05

Stein P, Vitavska O, Kind P, Hoppe W, Wieczorek H, Schurer NY. The biological basis for poly-L-lactic acid-induced augmen-tation. J Dermatol Sci. 2015; 78(1): 26-33. doi: 10.1016/j.jderm-sci.2015.01.012

Park S, Park KY, Yeo IK. Investigation of the degradation-re-tarding effect caused by the low swelling capacity of a novel hyal-uronic acid filler developed by solid-phase crosslinking technology. Ann Dermatol. 2014; 26(3): 357-362. doi: 10.5021/ad.2014.26.3.357

Tezel A, Fredrickson GH. The science of hyaluronic acid dermal fillers. J Cosmet Laser Ther. 2008; 10(1): 35-42. doi: Submit your article to this journal | https://openventio.org/online-manuscript-submission-system/ Original Research | Volume 6 | Issue 1 | Kajaia A, et al 10.1080/14764170701774901

Fakhari A, Berkland C. Applications and emerging trends of hyaluronic acid in tissue engineering, as a dermal filler, and in os-teoarthritis treatment. Acta Biomater. 2013; 9(7): 7081-7092. doi:

1016/j.actbio.2013.03.005 10. Da Costa A, Biccigo DGZ, de SouzaWeimann ET, et al. Dura-bility of three different types of hyaluronic acid fillers in skin: Are there differences among biphasic, bonophasic monodensified, and monophasic polydensified products? Aesthet Surg J. 2017; 37(5): 573-581. doi: 10.1093/asj/sjw161

Nestor MS. Facial lift and patient satisfaction following treat-ment with absorbable suspension sutures: 12-month data from a prospective, masked, controlled clinical study. J Clin Aesthet Derma-tol. 2019; 12(3): 18-26.

Bohnert K, Dorizas A, Lorenc P, Sadick NS. Randomized, controlled, multicentered, double-blind investigation of injectable poly-l-lactic acid for improving skin quality. Dermatol Surg. 2019; 45(5): 718-724. doi: 10.1097/DSS.0000000000001772

Kalyan R, Rafiq N, Wong V. The efficacy of polycaprolactone threads in zygomatic and mandibular lifting: Consecutive study from a single practitioner’s experience. Int J Clin Expl Dermatol. 2017; 1(1): 1-3. doi: 10.33140/ijced.02.01.08

El-Mesidy MS, Alaklouk WT, Azzam OA. Nasolabial fold cor-rection through cheek volume loss restoration versus thread lifting: A comparative study. Arch Dermatol Res. 2020; 312(7): 473-480. doi: 10.1007/s00403-019-02031-7

Tepavcevic B. Satisfaction of patients and surgeons with com-bined aptos thread lifting treatment, fat grafting and laser treat-ment. Aesthetic Plast Surg. 2024; 48(2): 116-121. doi: 10.1007/ s00266-022-03019-x

Goel A, Rai K. Non-surgical facelift-by PDO threads and der-mal filler: A case report. J Cosmet Dermatol. 2022; 21(10): 4241-4244. doi: 10.1111/jocd.14921

Published

2024-05-31

How to Cite

Albina Kajaia. (2024). Facial Rejuvenation and Patients Satisfaction with the Fourth Generation of Aptos P(LA/CL)–Hyaluronic Acid Threads: A 12-Month Study. Trichology and Cosmetology , 6(1), 7–15. https://doi.org/10.17140/tcoj-6-120