Single Dose Diclofenac and Tamsulosin Effectiveness in Patients Undergoing Double J-Stent Removal Under Local Anaesthesia

Abstract

Purpose
The purpose of this study was to see effectiveness of diclofenac sodium and tamsulosin combination on patients’ pain perception
after ureteral stent removal.
Materials and Methods
Study was carried out from October 2019 to March 2021. All patients with unilateral stent placement after renal or ureteric stone
endoscopic surgery were randomized in 3 groups. Group-A include 20 patients who were given placebo drug 2-hours prior to
double J (DJ) removal. Group-B included 20 patients who were given oral diclofenac 2-hours prior to DJ removal. Group-C
included 20 patients who were given oral diclofenac and tamsulosin 2-hours prior to DJ removal. All patients received 10 cc 2%
viscous lidocaine intraurethral before cystoscopy. No sedatives or analgesics were administered during the procedure. All patients
provided consent before the procedure and they were asked to record their pain experience on a visual analog pain scale as soon
as the procedure was finished. The pulse rate and systolic and diastolic blood pressure (BP) were also recorded 5-minutes before
the procedure and during the procedure
Results
General characteristic of age, gender and indication for DJ-stenting were comparable in all groups. The mean pain score on the
visual analogue scale (VAS) in Group-C was significantly lower than that in Group-A and B (p<0.001) A statistically significant
difference was found between the two groups in terms of anxiety scores after cystoscopy, intraoperative systolic BP and pulse rate.
Patients who were given oral diclofenac and tamsulosin two hours prior to DJ removal experienced less pain and anxiety.
Conclusion
Oral diclofenac plus tamsulosin combination prior to DJ removal improves patient’s comfort.