Nanotechnology Based Semen Purification: A Panacea

Abstract

With the inception of semen freezing technology, it has become possible to disseminate the superior germplasm through artificial insemination, which really revolutionized the
dairy industry. However, production of high quality sperm insemination dose is crucial to the
survival of this technology. Cryopreservation of sperm is a damaging phenomenon resulting in
about 50% drop in the quality from pre-freeze to post-thaw.1
One of the pre-dominant contributor to this damage is the presence of dead sperm which act as a source of free radical generation in the semen. The Reactive Oxygen Species (ROS) cause an oxidative injury to the viable
sperm, hence removal of such sperm from the semen could lead to improvement in the quality.
To this, nanotechnology based semen purification offers an efficient way to eliminate the dead
and/or prematurely capacitated spermatozoa from the semen.