Case Report Using 4% Fucoidan Cream for Recurrent Oral Herpes Labialis: Patient Symptoms Markedly Improved in Terms of Time to Healing and Time to Loss of Discomfort

Abstract

Recurrent oral herpes labialis (ROHL) is a rather widespread oral ulcerative condition with an unclear etiology. The clinical
characteristics of ROHL have been defined and therapies include systemic drugs and topical application of ointment to the lips.
However, these approaches have not been rigorously evaluated. Persistent, painful ROHL was successfully treated with fucoidan
in two patients. This study investigated the time required to complete healing and loss of discomfort. Two patients used Power
Fucoidan CreamTM (PFC) (4% fucoidan cream). ROHL was markedly improved by Power Fucoidan Cream in terms of both
time to healing and time to loss of discomfort. Further clinical trials are needed to confirm the value and safety of topical Power
Fucoidan Cream for treating ROHL.