Systemic Lupus Erythematosus as a Risk Factor for Cervical Cancer and its Precursor Conditions: Assessment Using Pap Smear and Histopathology

Authors

  • Mai A. Gobran
  • Soheir El-Ghoneimey
  • Safaa A. S. Ibrahim
  • Sabah Mohamedhanafy

Keywords:

Systemic lupus erythematosus (SLE), Cancer, Cervix, Low grade squamous intra-epithelial lesions, High grade squamous-intra epithelial lesions, Cervical, Intraepithelial neoplasia, Squamous cell carcinoma

Abstract

Background
Cancer of the cervix is a common cause of malignancy. Its association with systemic lupus erythematosus (SLE) is debatable.
Objective
Early detection of cervical pre-neoplastic lesion in SLE patients.
Method
A case control study was performed on 64 SLE group and 64 control group using a colposcopy, pap smear and histopathological examination.
Conclusion
This study revealed that preneoplastic and neoplastic lesions of the cervix were higher in the SLE group.

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Published

2022-08-03