Systemic Lupus Erythematosus as a Risk Factor for Cervical Cancer and its Precursor Conditions: Assessment Using Pap Smear and Histopathology

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Authors

  • Mai A. Gobran Department of Pathology, Zagazig University, Ash Sharqiyah Governorate, Egypt
  • Soheir El-Ghoneimey Department of Dermatology and Venereology, Zagazig University, Ash Sharqiyah Governorate, Egypt
  • Safaa A. S. Ibrahim Department of Obstetrics and Gynecology, Zagazig University, Ash Sharqiyah Governorate, Egypt
  • Sabah Mohamedhanafy Department of Pathology, Zagazig University, Ash Sharqiyah Governorate, Egypt

DOI:

https://doi.org/10.17140/GOROJ-8-155

Keywords:

Systemic lupus erythematosus (SLE), Cancer, Cervix, Low grade squamous intra-epithelial lesions, High grade squamous-intra epithelial lesions, Cervical, Intraepithelial neoplasia, Squamous cell carcinoma

Abstract

Background
Cancer of the cervix is a common cause of malignancy. Its association with systemic lupus erythematosus (SLE) is debatable.
Objective
Early detection of cervical pre-neoplastic lesion in SLE patients.
Method
A case control study was performed on 64 SLE group and 64 control group using a colposcopy, pap smear and histopathological examination.
Conclusion
This study revealed that preneoplastic and neoplastic lesions of the cervix were higher in the SLE group.

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Published

2022-08-03

How to Cite

Mai A. Gobran, Soheir El-Ghoneimey, Safaa A. S. Ibrahim, & Sabah Mohamedhanafy. (2022). Systemic Lupus Erythematosus as a Risk Factor for Cervical Cancer and its Precursor Conditions: Assessment Using Pap Smear and Histopathology. Gynecology and Obstetrics Research, 8(1), 1–7. https://doi.org/10.17140/GOROJ-8-155