Beneficial Effects of Pre-Operative Intra Aortic Balloon Pump Support in High Risk Patients Undergoing Coronary Artery Bypass Graft Surgery
DOI:
https://doi.org/10.17140/HROJ-4-137Keywords:
Intra-aortic balloon pump, ; Coronary artery bypass grafting, Coronary artery diseaseAbstract
Objective: The purpose of this study was to evaluate the efficacy and the cost-benefit of preoperative
Intra-aortic Balloon Pump (IABP) treatment on peri- and post-operative cardiac performance,
improved hemodynamic stability, reduced mortality and morbidity and the optimal
timing in high-risk patients undergoing Coronary Artery Bypass Grafting (CABG), when compared
to patients who did not receive IABP therapy.
Methods: Between January 2011 and June 2012, a total of 1149 patients underwent CABG at
our institution of which IABP was inserted in 90 patients, out of which 30 patients satisfied
the inclusion criteria. Out of 30 patients 10 had IABP insertion pre-operative, 10 had intraoperative,
and 10 had post-operative period. Euro score additive and logistic were comparable
in all the three groups to determine the benefit of using IABP prior to operation.
Results: Inotropic support in pre-IABP group is less as compared to intra- and post-IABP group
(p<0.02). The mean duration of ICU stay was more in intra-operative and post-operative IABP
group (p<0.28). No hospital mortality in pre-operative IABP group (0/10), 2 patient died in
intra-operative IABP group (2/10), 3 died in post-operative IABP group (3/10).
Conclusions: This study demonstrated pre-operative IABP therapy is an efficient and safe supportive
modality which significantly decreases the risk for hemodynamic instability in highrisk
patients undergoing CABG, improved cardiac performance, reduced inotropic requirements,
lower rate of hospital mortality and less post-operative morbidity, improve survival
and shortens both ICU and hospital length of stay significantly and is therefore cost effective.
Further studies with inclusion of more cases are required to verify our findings.
References
Dietl CA, Berkheimer MD, Woods EL, et al. Efficacy and cost-effectiveness of preoperative IABP in patients with ejection fraction of 0.25 or less. Ann Thorac Surg. 1996; 62(2): 401-409. doi: 10.1016/0003-4975(96)00244-5
Christenson JT, Badel P, Simonet F, Schmuziger M. Preopera-tive intraaortic balloon pump enhances cardiac performance and improves the outcome of redo CABG. Ann Thorac Surg. 1997; 64(5): 1237-1244. doi: 10.1016/S0003-4975(97)00898-9
Arafa OE, Pedersen TH, Svennevig JL, Fosse E, Geiran OR. Intraaortic balloon pump in open heart operations: 10-year fol-low-up with risk analisis. Ann Thorac Surg. 1998; 65(3): 741- 747. doi: 10.1016/S0003-4975(97)01385-4
Christenson JT, Somonet F, Badel P, Schmuziger M. Optimal timing of preoperative intaaortic balloon pump support in high-risk coronary patients. Ann Thorac Surg. 1999; 68(3): 934-939. doi: 10.1016/S0003-4975(99)00687-6
Gutfinger DE, Ott RA, Miller M, et al. Aggressive preopera-tive use of intraaortic balloon pump in elderly patients under-going coronary artery bypass grafting. Ann Thorac Surg. 1999; 67(3): 610-613. doi: 10.1016/S0003-4975(98)01201-6
Craver JM, Murrah CP. Elective intraaortic balloon counter-pulsation for high-risk off-pump coronary artery bypass. Ann Thorac Surg. 2001; 71(4): 1220-1223. doi: 10.1016/S0003- 4975(00)02685-0
Kim KB, Lim C, Ahn H, Yang JK. Intraaortic balloon pump therapy facilitates posterior vessel off-pump coronary artery bypass grafting in high-risk patients. Ann Thorac Surg. 2001; 71(6): 1964-1968. doi: 10.1016/S0003-4975(01)02638-8
Beauford RB, Goldstein DJ, Sardari FF, et al. Multivessel off-pump revascularization in octogenarians: Early and midterm outcomes. Ann Thorac Surg. 2003; 76(1): 12-17. doi: 10.1016/ S0003-4975(03)00014-6
Tasdemir O, Vural KM, Kargoz H, Bayazit K. Coronary artery bypass grafting on the beating heart without the use of extracor-poreal circulation, review of 2052 cases. J Thorac Cardiovasc Surg. 1998; 116(1): 68-73. doi: 10.1016/S0022-5223(98)70244-
Christenson JT, Maurice J, Simonet F, et al. Effect of low left ventricular ejection fractions on outcome of primary coronary bypass grafting in end-stage coronary artery disease. J Cardiovasc Surg (Torino). 1995; 36(1): 45-51. Web site. http:// europepmc.org/abstract/med/7721925. Accessed January 25, 2017.
Nashef SA, Roques F, Michel P, Gauducheau E, Lemeshow S, Salamon R. European system for cardiac operative risk evaluation (EuroSCORE). Eur J Cardiothorac Surg. 1999; 16(1): 9-13. doi: 10.1016/S1010-7940(99)00134-7
Mair J, Larue C, Mair P, et al. Use of cardiac troponin I to diagnose perioperative myocardial infarction in coronary artery bypass grafting. Clin Chem. 1994; 40(11): 2066-2070. Web site. http://clinchem.aaccjnls.org/content/40/11/2066.short. Accessed January 25, 2017.
Creswell LL, Rosenbloom M, Cox JL, et al. Intraaortic balloon counterpulsation: Patterns of usage and outcome in cardiac surgery patients. Ann Thorac Surg. 1992; 54(1): 11-20. doi: 10.1016/0003-4975(92)91133-T
Torchiana DF, Hirsch G, Buckley MJ, et al. Intraaortic bal-loon pumping for cardiac support: Trends in practice and out-come, 1968 to 1995. J Thorac Cardiovasc Surg. 1997; 113(4): 758-769. doi: 10.1016/S0022-5223(97)70235-6
Kang N, Edwards M, Larbalestier R. Preoperative intraaortic balloon pumps in high-risk patients undergoing open heart sur-gery. Ann Thorac Surg. 2001; 72(1): 54-57. doi: 10.1016/S0003- 4975(01)02700-X
Tedoriya T, Kawasuji M, Sakakibara N, Takemura H, Watanabe Y, Hetzer R. Coronary bypass flow during use of intraaortic balloon pumping and left ventricular assist device. Ann Thorac Surg. 1998; 66(2): 477-481. doi: 10.1016/S0003- 4975(98)00468-8
Gunstensen J, Goldman BS, Scully HE, Huckell VF, Adel-man AG. Evolving indications for preoperative intraaortic bal-loon pump assistance. Ann Thorac Surg. 1976; 22(6): 535-545. doi: 10.1016/S0003-4975(10)64472-4
Kloner RA, Rezkalla SH. Cardiac protection during acute myocardial infarction: Where do we stand in 2004? J Am Coll Cardiol. 2004; 44(2): 276-286.
Lee DC, Ting W, Oz MC. Myocardial revascularization after acute myocardial infarction. In: Cohn LH, Edmunds LH Jr, eds. Cardiac Surgery in the Adult. New York, USA: McGraw-Hill; 2003: 639 -658.
Fasseas P, Cohen M, Kopistansky C, et al. Pre-operative intra-aortic balloon counterpulsation in stable patients with left main coronary disease. J Invas Cardiol. 2001; 13(10): 679-683. Web site. http://europepmc.org/abstract/med/11731684. Ac-cessed January 25, 2017.
Wyse RK, Taylor KM. Using the STS and multinational car-diac surgical databases to establish risk-adjusted benchmarks for clinical outcomes. Heart Surg Forum. 2002; 5(3): 258-264.
Meharwal ZS, Trehan N. Vascular complications of in-traaortic balloon insertion in patients undergoing coronary re-vascularization: Analysis of 911 cases. Eur J Cardiothorac Surg. 2002; 21(4): 741-747. doi: 10.1016/S1010-7940(02)00 034-9
Downloads
Published
How to Cite
Issue
Section
License

This work is licensed under a Creative Commons Attribution 4.0 International License.
All content published in Heart Research (HROJ) is licensed under the Creative Commons Attribution 4.0 International License (CC BY 4.0). This license allows anyone to copy, distribute, transmit, and adapt the work — including for commercial purposes — provided appropriate credit is given to the original author(s) and source.