A Noteworthy Case of Myasthenic Crisis Induced by Levofloxacin

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Authors

  • Ada Young West Virginia University (WVU),Wheeling Hospital,Wheeling,WV 26003, USA
  • Ramya Ramesh West Virginia University (WVU),Wheeling Hospital,Wheeling,WV 26003, USA
  • Milind Awale West Virginia University (WVU),Wheeling Hospital,Wheeling,WV 26003, USA

DOI:

https://doi.org/10.17140/imoj-8-124

Keywords:

Myasthenia gravis, Levofloxacin, Fluoroquinolones, Neuromuscular junction, Myasthenic crisis, Myasthenia Gravis Founda tion of America (MGFA) clinical classification, Antibiotic-induced exacerbation, Ocular muscle weakness, Respiratory muscle involvement, Treatment strategies, Molecular mechanisms, Adverse drug reactions, The coding symbols for a thesaurus of adverse reaction terms ( COSTART) frequency classification

Abstract

This case report discusses a patient with a past medical history of Myasthenia gravis who was admitted to the hospital for community-acquired pneumonia and was then sent into a myasthenic crisis secondary to treatment with Levofloxacin. Although Levofloxacin can be effective at resolving community-acquired pneumonia, this antibiotic can precipitate muscular pathologies in certain population subsets. This is an interesting case of an acute myasthenic crisis being induced by Levofloxacin, leading the patient into acute hypoxic respiratory failure. It is critical to thoroughly consider, and if possible, avoid, any class of medications that may affect muscular function in individuals with myasthenia gravis.

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Published

2024-04-26

How to Cite

Ada Young, Ramya Ramesh, & Milind Awale. (2024). A Noteworthy Case of Myasthenic Crisis Induced by Levofloxacin. Internal Medicine, 8(1), 4–7. https://doi.org/10.17140/imoj-8-124