Effects of Dietary Control, Exercise and Anti-Obesity Prescriptions on Weight Loss: An Interview-Based Study

Authors

  • Hala M. Demerdash Department of Clinical Pathology, Alexandria University Hospitals, Alexandria University, Pharmacology and Toxicology Department, Faculty of Pharmacy and Drug Manufacturing, Pharos University, Alexandria, Egypt; Pharmacology and Toxicology Department, Faculty of Pharmacy and Drug Manufacturing, Pharos University, Alexandria, Egypt
  • Sherine Abdel Hady Pharmacology and Toxicology Department, Faculty of Pharmacy and Drug Manufacturing, Pharos University, Alexandria, Egypt
  • Lamia Said Kandil Pharmacology and Toxicology Department, Faculty of Pharmacy and Drug Manufacturing, Pharos University, Alexandria, Egypt

DOI:

https://doi.org/10.17140/OROJ-5-135

Keywords:

Obesity; Overweight; Body mass index; Physical activity; Anti-obesity prescriptions

Abstract

Obesity is a major public health problem all over the world. The objective of this work was to evaluate effectiveness of various weight
management strategies.
Methods
A clinic interview-based study was accomplished in various nutrition clinics in Alexandria city and pursued the following data: demographic data, body mass index (BMI), lipid profile, comorbidities, with emphasize on the authenticity of the effectiveness of weight
management strategies.
Results
The study comprised 2,240 participants following weight management strategies at nutrition clinics; 59.8% were obese (group I) and
40.2% were overweight (group II). BMI was highest among age group 30-40 years in group I and 18-20 years in group II.
Weight management strategy by dietary control merely in 55.8% of group I and 59.5% of group II. 33.5% of group I implemented
exercise training plan and 41.5% of group II respectively. Fourteen point seven percentage of group I responded to adjuvant antiobesity drug versus 1.5% of group II. The most commonly adopted anti-obesity prescription was Orlistat.
Conclusion
Participants who received anti-obesity prescriptions combined with dietary control and exercise obtained the best results when compared to other strategies, therefore anti-obesity prescriptions may be beneficial in conditions that are resistant to other weight management strategies. Comorbidities, particularly dyslipidemia; may partially impede effective obesity management protocols.

References

Kite J, Grunseit A, Bohn-Goldbaum E, et al. A systematic search and review of adult-targeted overweight and obesity prevention mass media campaigns and their evaluation: 2000-2017.J Health Com-mun. 2018; 23(2): 207-232. doi: 10.1080/10810730.2018.1423651

Yanovski SZ, Yanovski JA. Toward precision approaches for the prevention and treatment of obesity. JAMA. 2018; 319(3): 223- 224. doi: 10.1001/jama.2017.20051

Afshin A, Forouzanfar M, Reitsma M, et al. Health effects of overweight and obesity in 195 countries over 25-years. N Engl J Med. 2017; 377: 13-27. doi: 10.1056/NEJMoa1614362

El Rhazi K, Nejjari C, Zidouh A, et al. Prevalence of obesi-ty and associated sociodemographic and lifestyle factors in Mo-rocco. Public Health Nutr. 2011; 14(1): 160-167. doi: 10.1017/ S1368980010001825

Vetter ML, Faulconbridge LF, Webb VL, Wadden TA. Behav-ioral and pharmacologic therapies for obesity. Nat Rev Endocrinol. 2010; 6: 578-588. doi: 10.1038/nrendo.2010.121

James W, Caterson I, Coutinho W, et al. Effect of sibutramine on cardiovascular outcomes in overweight and obese subjects. N Engl J Med. 2010; 363: 905-917. doi: 10.1056/NEJMoa1003114

Zimmet PZ, Alberti KG. Introduction: Globalization and the non-communicable disease epidemic. Obesity (Silver Spring). 2006; 14: 1-3. doi: 10.1038/oby.2006.1

Astrup A, Madsbad S, Breum L, et al. Effect of tesofensine on bodyweight loss, body composition, and quality of life in obese pa-tients: a randomised, double-blind, placebo-controlled trial. Lancet. Original Research | Volume 5 | Number 1| 2008; 372: 1906-1913. doi: 10.1016/S0140-6736(08)61525-1

Shai I, Schwarzfuchs D, Henkin Y, et al. Weight loss with a low-carbohydrate, Mediterranean, or low-fat diet. NEJM. 2008; 359 (3): 229-241.

Ekelund U, Sepp H, Brage S, et al. Criterion-related validity of the last 7-day, short form of the international physical activ-ity questionnaire in swedish adults. Public Health Nutr. 2006; 9(2): 258-265.

Aitsi-Selmi A, Chandola T, Friel S, et al. Interaction between education and household wealth on the risk of obesity in wom-en in Egypt. PloS One. 2012; 7(6): e39507. doi: 10.1371/journal. pone.0039507

Alsheikh-Ali AA, Omar MI, Raal FJ, et al. Cardiovascular risk factor burden in africa and the middle east: The Africa middle east cardiovascular epidemiological (ACE) study. PloS one. 2014; 9(8): e102830. doi: 10.1371/journal.pone.0039507

Musaiger AO. Diet and prevention of coronary heart disease in the Arab Middle East countries. Med Princ Pract. 2002; 11: 9-16. doi: 10.1159/000066415

Flegal KM, Kit BK, Orpana H, Graubard BI. Association of all-cause mortality with overweight and obesity using standard body mass index categories: A systematic review and meta-analysis. JAMA. 2013; 309: 71-82. doi: 10.1001/jama.2012.113905

Manyanga T, El-Sayed H, Doku D, Randall J. The prevalence of underweight, overweight, obesity and associated risk factors among school-going adolescents in seven African countries. BMC Public Health. 2014; 14: 887. doi: 10.1186/1471-2458-14-887

Popkin BM, Lu B, Zhai F. Understanding the nutrition tran-sition: Measuring rapid dietary changes in transitional countries. Public Health Nutr. 2002; 5: 947-953. doi: 10.1079/PHN2002370

Yasin A. Time expenditure in egyptian community cairo: Na-tional center for social and crime studies 1998 (in Arabic). Annals of Alquds Medicine. 2013: 9 (1435): 13-21.

Walley A, Blakemore A, Froguel P. Genetics of obesity and the prediction of risk for health. Hum Mol Genet. 2006; 15 Spec No 2: R124-R130. doi: 10.1093/hmg/ddl215

Merchant AT, Anand SS, Kelemen LE, et al. Carbohydrate in-take and HDL in a multiethnic population. Am J Clin Nutr. 2007; 85(1): 225-230. doi: 10.1093/ajcn/85.1.225

Liu S, Manson J, Stampfer M, et al. Dietary glycemic load as-sessed by food-frequency questionnaire in relation to plasma high-density-lipoprotein cholesterol and fasting plasma triacylglycerols Submit your article to this journal | https://openventio.org/submit-manuscript/ Original Research | Volume 5 | Number 1| Demerdash HM, et al. in postmenopausal women. Am J Clin Nutr. 2001; 73: 560-566. doi: 10.1093/ajcn/73.3.560

Anderson JW, Konz EC, Frederich RC, Wood CL. Long-term weight loss maintenance: A meta-analysis of US studies. Am J Clin Nutr. 2001; 74: 579-584. doi: 10.1093/ajcn/74.5.579

Maclean PS, Bergouignan A, Cornier MA, Jackman MR. Biolo-gy’s response to dieting: the impetus for weight regain. Am J Physiol Regul Integr Comp Physiol. 2011; 301(3): R581-R600. doi: 10.1152/ ajpregu.00755.2010

Redman L, Heilbronn L, Martin C, et al. Effect of calorie restriction with or without exercise on body composition and fat distribution. J Clin Endocrinol Metab. 2007; 92(3): 865-872. doi: 10.1210/jc.2006-2184

Hemmingsson E, Johansson K, Eriksson J, et al. Weight loss and dropout during a commercial weight-loss program including a very-low-calorie diet, a low-calorie diet, or restricted normal food: Observational cohort study. Am J Clin Nutr. 2012; 96: 953-961. doi: 10.3945/ajcn.112.038265

Larson-Meyer D, Redman L, Heilbronn L, Martin C, Ravus-sin E. Caloric restriction with or without exercise: The fitness ver-sus fatness debate. Med Sci Sports Exerc. 2010; 42: 152-159. doi: 10.1249/MSS.0b013e3181ad7f17

Malis C, Rasmussen EL, Poulsen P, et al. Total and regional fat distribution is strongly influenced by genetic factors in young and elderly twins. Obes Res. 2005; 13: 2139-2145. doi: 10.1038/ oby.2005.265

Santos-Pinto FN, Luz J, Griggio MA. Energy expenditure of rats subjected to long-term food restriction. Int J Food Sci Nutr. 2001; 52(2): 193-200.

Panagiotakos D, Pitsavos C, Chrysohoou C, Skoumas J, Stefa-nadis C. Status and management of blood lipids in Greek adults and their socio-demographic, life-style and dietary factors: The ATTICA study. Blood lipid distribution in Greece. Atherosclerosis. 2004; 173(2): 351-361. doi: 10.1016/j.atherosclerosis.2003.12.031

Chanoine J, Hampl S, Jensen C, Boldrin M, Hauptman J. Effect of orlistat on weight and body composition in obese adolescents: A randomized controlled trial. JAMA. 2005; 293(23): 2873-2883. doi: 10.1001/jama.293.23.2873

Scheen AJ. Current management strategies for coexisting dia-betes mellitus and obesity. Drugs. 2003; 63: 1165-1184.

Bray G, DeLany J. Opinions of obesity experts on the causes and treatment of obesity: A new survey. Obes Res. 1995; 3(4): 419S-423S.

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Published

2019-09-28

How to Cite

Hala M. Demerdash, Sherine Abdel Hady, & Lamia Said Kandil. (2019). Effects of Dietary Control, Exercise and Anti-Obesity Prescriptions on Weight Loss: An Interview-Based Study. Obesity Research, 11–17. https://doi.org/10.17140/OROJ-5-135

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