A Rare Cutaneous Manifestation of the Systemic Erythematosus Lupus: The Chilblain Lupus – A Clinical Case

Authors

  • David Castro-Corredor Department of Rheumatology, General University Hospital of Ciudad Real, Ciudad Real, Spain
  • Prado Sánchez-Caminero Department of Dermatology, General University Hospital of Ciudad Real, Ciudad Real, Spain
  • Isabel M. de Lara-Simón Department of Pathology, General University Hospital of Ciudad Real, Ciudad Real, Spain
  • Fiorella L. Piaggio-Muente Department of Family and Communitary, General University Hospital of Ciudad Real, Ciudad Real, Spain

DOI:

https://doi.org/10.17140/ORHOJ-3-112

Keywords:

Chilblain lupus; Perniosis; Chilblain pernio; Rare cutaneous; Myelomonocytic leukemia; Systemic Lupus Erythematosus.

Abstract

Perniosis or chilblain pernio is an inflammatory skin disease, typically located on acral skin surfaces secondary to prolonged expo-sure to cold temperatures and damp conditions. This disorder can appear as an idiopathic dermatosis, usually in young women, but occasionally it is associated with diseases such as anorexia, intestinal lymphoma, chronic myelomonocytic leukemia, monoclonal gammopathies, cryoproteinaemia, viral infections, as well as connective tissue diseases, especially lupus, picture that is known as chilblain lupus. We present a case of perniosis associated with Systemic Lupus Erythematosus and review the literature.

References

Hedrich CM, Fiebig B, Hauck FH, et al. Chilblain lupus erythe-matosus--a review of literature. Clin Rheumatol. 2008; 27(8): 949- 954. doi: 10.1007/s10067-008-0942-9

Millard LG, Rowell NR. Chilblain lupus erythematosus (Hutchin-son). A clinical and laboratory study of 17 patients. Br J Dermatol. 1978; 98(5): 497-506. doi: 10.1111/j.1365-2133.1978.tb01935.x

Takci Z, Vahaboglu G, Eksioglu H. Epidemiological patterns of perniosis and its association with systemic disorder. Clin Exp Der-matol. 2012; 37(8): 844-849. doi: 10.1111/j.1365-2230.2012.04435.x

Su WP, Perniciaro C, Rogers RS 3rd, White JW Jr. Chilblain lupus erythematosus (lupus pernio): Clinical review of the Mayo Clinic experience and proposal of diagnostic criteria. Cutis. 1994; 54(6): 395-399.

Viguier M, Pinquier L, Cavelier-Balloy B, et al. Clinical and histo-pathologic features and inmunologic variables in patients with se-vere chilblain. A study of the relationship to lupus erythematosus. Medicine (Baltimore). 2001; 80(3): 180-188. doi: 10.1097/00005792- 200105000-00004

Boada A, Bielsa I, Fernández-Figueras MT, Ferrándiz C. Per-niosis: clinical and histopathological analysis. Am J Dermatopathol. 2010; 32(1): 19-23. doi: 10.1097/DAD.0b013e3181af1d24

Cribier B, Djeridi N, Peltre B, Grosshans E. A histologic and im-munohistochemical study of chilblains. J Am Acad Dermatol. 2001; 45(6): 924-929. doi: 10.1067/mjd.2001.117861

Downloads

Published

2025-09-11

How to Cite

David Castro-Corredor, Prado Sánchez-Caminero, Isabel M. de Lara-Simón, & Fiorella L. Piaggio-Muente. (2025). A Rare Cutaneous Manifestation of the Systemic Erythematosus Lupus: The Chilblain Lupus – A Clinical Case. Osteology and Rheumatology, 3(1), 4–6. https://doi.org/10.17140/ORHOJ-3-112

Issue

Vol. 3 No. 1 (2020): Volume 3 Issue 1 2020

Section

Articles

License

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

All content published in Osteology and Rheumatology (OROJ) is licensed under the Creative Commons Attribution 4.0 International License (CC BY 4.0). This license allows anyone to copy, distribute, transmit, and adapt the work — including for commercial purposes — provided appropriate credit is given to the original author(s) and source.

Most read articles by the same author(s)