Neonatal Hyperoxia and Pulmonary Hypertension

Authors

  • Miranda Sun and Qiwei Yang

DOI:

https://doi.org/10.17140/PNNOJ-1-101

Abstract

ABBREVIATIONS: ACh: Acetylcholine; ALK: Activin-like Kinase; BMP: Bone Morphogenetic
Protein; BMPR2: BMP Receptor type II; BPD: Bronchopulmonary Dysplasia; cGMP: Cyclic
Guanosine Monophosphate; ETA-R: Endothelin Receptor type A; ETB-R: Endothelin Receptor
type B; LRP: Low-density lipoprotein Receptor-related Protein; MYPT1: Myosin-associated
Phosphatase Type I; NO: Nitric Oxide; PASMC: Pulmonary Artery Smooth Muscle Cell; PDE:
Phosphodiesterase; PH: Pulmonary Hypertension; PPHN: Persistent Pulmonary Hypertension
of the Newborn; RVH: Right Ventricular Hypertrophy; sGC: Soluble Guanylate Cyclase;
TGF-β: Transforming Growth Factor-β; WISP: Wnt-induced Secreted Protein.

References

Gore A, Muralidhar M, Espey MG, Degenhardt K, Mantell LL. Hyperoxia sensing: from molecular mechanisms to significance in disease. Journal of immunotoxicology. 2010; 7(4): 239-254. doi: 10.3109/1547691X.2010.492254

Mourani PM, and Abman SH. Pulmonary vascular disease in bronchopulmonary dysplasia: pulmonary hypertension and beyond. Current Opinion in Pediatrics. 2013; 25(3): 329-337. doi: 10.1097/ MOP.0b013e328360a3f6

Velten M, Britt RD, Jr., Heyob KM, et al. Prenatal inflamma tion exacerbates hyperoxia-induced functional and structural changes in adult mice. American Journal of Physiology Regulatory, Integrative and Comparative Physiology. 2012; 303(3): R279- - 290.

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Published

2014-04-04

How to Cite

Miranda Sun and Qiwei Yang. (2014). Neonatal Hyperoxia and Pulmonary Hypertension. Pediatrics and Neonatal Nursing, 1(1), 1–5. https://doi.org/10.17140/PNNOJ-1-101