Quick Diagnosis: The Key for a Positive Outcome in Malignant Hyperthermia—A Case Report

Authors

  • João M. H. F. Moniz Department of Anesthesiology, Portuguese Institute of Oncology Francisco Gentil, Lisbon Portugal, Rua Francisco Tomás da Costa, n45, RC 1600-092, Lisbon, Portugal
  • Rita Ferreira Department of Anesthesiology, Instituto Português de Oncologia de Lisboa, R. Prof. Lima Basto, Lisboa, Portugal
  • Nuno Serrano Department of Anesthesiology, Portuguese Institute of Oncology Francisco Gentil, Lisbon Portugal, Rua Francisco Tomás da Costa, n45, RC 1600-092, Lisbon, Portugal
  • Ana S. Cunha Department of Anesthesiology, Champalimaud Foundation Clinical Centre, Lisbon, Portugal

DOI:

https://doi.org/10.17140/RPAOJ-7-133

Keywords:

Anesthesia, Malignant hyperthermia, Patient

Abstract

We report a likely case of malignant hyperthermia triggered by sevoflurane in a 15-year-old male during anesthesia for limb disarticulation surgery. Clinical suspicion was raised with the increasing end-tidal carbon dioxide (ETCO2) and heart rate after induction of general anesthesia. Quick diagnosis, early intervention and teamwork were essential for the positive outcome of this case, preventing the development of more severe complications such as acute kidney injury (AKI) or rhabdomyolysis. Clinical grading score deem this case “greater than likely” despite a negative genetic test. Other metabolic derangements related with the primary neoplasm cannot be excluded but there are no reports on the literature describing such an exuberant reaction. The authors wish to highlight the need of prompt diagnosis, which requires a high degree of suspicion, in order to deliver a positive outcome.

References

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Published

2023-02-09

How to Cite

João M. H. F. Moniz, Rita Ferreira, Nuno Serrano, & Ana S. Cunha. (2023). Quick Diagnosis: The Key for a Positive Outcome in Malignant Hyperthermia—A Case Report. Research and Practice in Anesthesiology, 7(1), 1–4. https://doi.org/10.17140/RPAOJ-7-133

Issue

Vol. 7 No. 1 (2023): Volume 7 Issue 1 2023

Section

Articles

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All content published in Research and Practice in Anesthesiology (RPA) is licensed under the Creative Commons Attribution 4.0 International License (CC BY 4.0). This license allows anyone to copy, distribute, transmit, and adapt the work — including for commercial purposes — provided appropriate credit is given to the original author(s) and source.