Blighted Ovum: A Case Report

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Authors

  • Aqsaa N. Chaudhry, MBA Saint James School of Medicine, Anguilla
  • Frederick M. Tiesenga, MD Chairman of Department of Surgery,West Suburban Medical Center, Oak Park, Illinois, USA
  • Sandeep Mellacheruvu, MD, MPH Director of Clinical Research, Loretto Hospital, Chicago, Illinois, USA
  • Ryan R. Sanni, MD Research Assistant of Clinical Sciences,Windsor University School of Medicine, Cayon, St. Kitts and Nevis

DOI:

https://doi.org/10.17140/WHOJ-6-135

Keywords:

termination, non-viable

Abstract

Presenting in her late twenties, this case report examines a G6P2 patient at 11-weeks gestation that was diagnosed with a blighted
ovum, as well as the subsequent outcome and methods of additional management. A blighted ovum refers to a fertilized egg that
does not develop, despite the formation of a gestational sac. The most common cause of a blighted ovum is of genetic origin.
Trisomies account for most first trimester miscarriages, while consanguineous marriages result in recurrent miscarriages due to
a blighted ovum. Additionally, a higher percentage of deoxyribonucleic acid (DNA) damage in sperm carries a higher rate of
miscarriage. Nutritional factors that may lead to a blighted ovum include low-levels of copper, prostaglandin E2, and anti-oxidative
enzymes. High body mass index (BMI), especially in women with a BMI≥30 kg/m2
has been shown to be linked to a blighted
ovum. Globally, it has been shown that a blighted ovum is a serious adverse event related to vaccination against dengue fever

References

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Chaudhry K, Siccardi MA. Blighted Ovum (Anembryonic Pregnancy). Bethesda, MD, USA: StatPearls Publishing LLC; 2019.

Henderson DJ, Bennett PR, Moore GE. Expression of hu-man chorionic gonadotrophin α and β subunits is depressed with early embryonic failure. Hum Reprod. 1992; 7(10): 1474-1478. doi: 10.1093/oxfordjournals.humrep.a137597

Al-Ma’ani W, Solomayer E-F, Hammadeh M. Expectant versus surgical management of first-trimester miscarriage: A randomized controlled study. Arch Gynecol Obstet. 2014; 289(5): 1011-1015. doi: 10.1007/s00404-013-3088-1 Case Report | Volume 6 | Number 1|

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Published

2020-02-02

How to Cite

Aqsaa N. Chaudhry, MBA, Frederick M. Tiesenga, MD, Sandeep Mellacheruvu, MD, MPH, & Ryan R. Sanni, MD. (2020). Blighted Ovum: A Case Report. Women’s Health, 3–4. https://doi.org/10.17140/WHOJ-6-135

Issue

Volume 6 Issue 1 2020

Section

Articles

License

Creative Commons License

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