Natural Killer (NK) Cells and Human Immunodeficiency Virus (HIV) Infection
DOI:
https://doi.org/10.17140/HARTOJ-3-120Keywords:
Natural Killer (NK), Human Immunodeficiency Virus (HIV) infection, VirusAbstract
Human Immunodeficiency Virus (HIV) infection has become a serious problem of public health. Recently, it is observed cellular immunity is involved in HIV infection and disease progression, especially the Natural Killer (NK) cells, which are important part of innate immunity. In order to clearly understand the mechanism of HIV infection, we try to figure out the function of NK cells during HIV infection. The article reviews the function of NK cells and the effect of NK cells in HIV infection.
References
Herberman RB, Nunn ME, Lavrin DH. Natural cytotoxic re-activity of mouse lymphoid cells against syngeneic acid allo-geneic tumors. I. Distribution of reactivity and specificity. Int J Cancer. 1975; 16(2): 216-229.
Mavilio D, Lombardo G, Benjamin J, et al. Characterization of CD56-/CD16+ natural killer (NK) cells: A highly dysfunc-tiona lNK subset expanded in HIV-infected viremic individu-als. Proc Natl Acad Sci USA. 2005; 102(8): 2886-2891. doi: 10.1073/pnas.0409872102
Jia M, Li D, Shao Y. Advance research on relationship be-tween NK cells and human immunodeficiency virus infection. Chinese Tropical Medicine. 2012; 12(4): 537-541.
Vivian JP, Duncan RC, Berry R, et al. Killer cell immunoglob-HIV/AIDS Res Treat Open J ulin-like receptor 3DL1-mediated recognition of human leuko-cyte antigen B. Nature. 2011; 479(7373): 401-405. doi: 10.1038/ nature10517
Fadda L, O’Connor GM, Kumar S, et al. Common HIV-1 pep-tide variants mediate differential binding of KIR3DL1 to HLA-Bw4 molecules. J Virol. 2011; 85(12): 5970-5974. doi: 10.1128/ JVI.00412-11
Jia M, Li D, He X, et al. Impaired natural killer cell-induced antibody-dependent cell-mediated cytotoxicity is associated with HIV-1 disease progression. Clin Exp Immunol. 2013; 171(1): 107-116. doi: 10.1111/j.1365-2249.2012.04672.x
Brackenridge S, Evans EJ, Toebes M, et al. An early HIV mu-tation within an HLA-B*57-restricted T cell epitope abrogates binding to the killer inhibitory receptor 3DL1. J Virol. 2011; 85(11): 5415-5422. doi: 10.1128/JVI.00238-11
Thananchai H, Makadzange T, Maenaka K, et al. Reciprocal recognition of an HLA-Cw4-restricted HIV-1 gp120 epitopeby CD8+ T cells and NK cells. AIDS. 2009; 23(2): 189-193. doi: 10.1097/QAD.0b013e32831fb55a
Yu XG, Addo MM, Perkins BA, et al. Differences in the ex-pressed HLA class I alleles effect the differential clustering of HIV type 1-specific T cell responses in infected Chinese and caucasians. AIDS Res Hum Retroviruses. 2004; 20(5): 557-564. doi: 10.1089/088922204323087813
Boulet S, Kleyman M, Kim JY, et al. A combined genotype of KIR3DL1 high expressing alleles and HLA-B*57 is associ-ated with a reduced risk of HIV infection. AIDS. 2008; 22(12): 1487-1491. doi: 10.1097/QAD.0b013e3282ffde7e
Downloads
Published
How to Cite
Issue
Section
License
This work is licensed under a Creative Commons Attribution 4.0 International License.
All content published in HIV/AIDS Research and Treatment (HRT) is licensed under the Creative Commons Attribution 4.0 International License (CC BY 4.0). This license allows anyone to copy, distribute, transmit, and adapt the work — including for commercial purposes — provided appropriate credit is given to the original author(s) and source.
