The Effect of Adenotonsillectomy on Mean Platelet Volume and Neutrophil-to-Lymphocyte Ratio

Abstract

Objectives: To explore the effect of adenotonsillectomy on mean platelet volume (MPV) lev-els and neutrophil to lymphocyte ratio (NLR) values in children with obstructive sleep apnea syndrome (OSAS).
Subjects and Methods: In total, 127 children (69 males, 58 females; average age 10.20±8.96 years; range, 5-18 years) who underwent adenotonsillectomy with a diagnosis of OSAS were included in the study. Pre-operative MPV levels and NLR values were compared with measurements in the post-operative third month. A p-value <0.05 was considered to reflect statistical significance.
Results: Mean pre-operative MPV values were 8.12±1.28 femtoliters (fL) and mean post-operative MPV values were 7.96±1.01 fL, respectively. Post-operative MPV values were significantly lower than pre-operative measurements (p=0,028, p<0.05). Mean pre-operative NLR levels were 1.46±0.82 and post-operative NLR values were 1.42±1.01, respectively. Post-operative NLR values were significantly lower than pre-operative NLR values (p=0.032, p<0.05).
Conclusion: We observed statistically significant lower MPV levels and NLR values after ad-enotonsillectomy in children with OSAS. Future randomized studies should explore the relationship between the MPV levels, NLR values and parameters in polysomnography in larger numbers of patients with OSAS.