Interactions of Immunomodulatory HLA-G with Immune Cells during Pregnancy and Endometriosis

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Authors

  • Parveen Parasar Boston Center for Endometriosis, Brigham and Women’s Hospital, Boston Children’s Hospi-tal, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA

DOI:

https://doi.org/10.17140/GOROJ-2-121

Abstract

The Major Histocompatibility Complex (MHC), the genetic region that encodes the proteins responsible for tissue graft rejection,1 encodes MHC Class I (MHC-I) and MHC Class II (MHC-II) glycoproteins. There are two subclasses of MHC-I proteins. Classical MHC-I (MHC-Ia) proteins are membrane-bound isoforms that are expressed in all nucleated cells of the body and present intracellular pathogen-derived peptides or the animal’s own peptides on the cell surface for immune recognition by CD8 T cells.

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Published

2015-12-01

How to Cite

Parveen Parasar. (2015). Interactions of Immunomodulatory HLA-G with Immune Cells during Pregnancy and Endometriosis. Gynecology and Obstetrics Research, 2(4), 93–95. https://doi.org/10.17140/GOROJ-2-121