Female Genital Schistosomiasis: A Neglected Tropical Disease
DOI:
https://doi.org/10.17140/GOROJ-3-134Keywords:
Female genital schistosomiasis, Neglected disease, Morbidity, Mortality, Life threateningAbstract
Female genital schistosomiasis is a neglected tropical disease. Few clinicians consider it in their differential diagnosis. Yet this disease affects hundreds of millions of people. Hundreds of thousands of them actually die annually. It significantly affects the reproductive health of women. Patients infected in childhood may carry the burden of disease throughout their lives without being detected. Global attention is occupied by new emerging diseases like Zika virus and female genital schistosomiasis is relegated to back of pages in the list of global worries. The importance of this disease on the health of women cannot be over-emphasied. The global attention must be focused so that it can be tackled adequately. Awareness among clinicians must be increased so that they consider it when women present to them with unusual symptomatology. Female genital schistosomiasis is a neglected tropical disease affecting millions of people. It causes significant morbidity and mortality in women. Awareness among clinicians is low as most cases are discovered fortuitously while undergoing investigations for other conditions.
References
Vennervald BJ, Dunne DW. Morbidity in schistosomia-sis: An update. Curr Opin Infect Dis. 2004; 17(5): 439-447. Web site. http://journals.lww.com/co-infectiousdiseases/Ab-stract/2004/10000/Morbidity_in_schistosomiasis__an_update. 9.aspx. Accessed August 29, 2016
Aminu MB, Abdullahi K, Dattijo LM. Tubal ectopic gesta-tion associated with genital schistosomiasis: A case report. Afr J Reprod Health. 2014; 18(2): 144-146. Web site. http://www. ajol.info/index.php/ajrh/article/view/104437. Accessed August 29, 2016
Shebel HM, Elsayes KM, Abou El Atta HM, Elguindy YM, El-Diasty TA. Genitourinary schistosomiasis: Life cycle and ra-diologic-pathologic findings. Radiographics. 2012; 32(4): 1031- 1046. doi: 10.1148/rg.324115162
Delmondes LM, Cruz MA, Guimaraes MK, Santana LG, Gon-calves VP, Brito HL. Endocervical schistosomiasis: Case report. Rev Bras Ginecol Obstet. 2014; 36(6): 276-280. doi: 10.1590/ S0100-720320140004827
Pillay P, van Lieshout L, Taylor M, et al. Cervical cytology as a diagnostic tool for female genital schistosomiasis: Correlation to cervical atypia and Schistosoma polymerase chain reaction. Cytojournal. 2016; 13: 10. doi: 10.4103/1742-6413.180784
Toller A, Scopin AC, Apfel V, et al. An interesting finding in the uterine cervix: Schistosoma haematobium calcified eggs. Autops Case Rep. 2015; 5(2): 41-44. doi: 10.4322/acr.2015.003
Hegertun IE, Sulheim Gundersen KM, Kleppa E, et al. S hae-matobium as a common cause of genital morbidity in girls: A cross-sectional study of children in South Africa. PloS Negl Trop Dis. 2013; 7(3):e2104. doi: 10.1371/journal.pntd.0002104
Holmen S, Galappaththi-Arachchige HN, Kleppa E, et al. Characteristics of blood vessels in female genital schistosomia-sis: Paving the way for objective diagnostics at the point of care. PloS Negl Trop Dis. 2016; 10(4): e0004628. doi: 10.1371/jour-nal.pntd.0004628
Kjetland EF, Hegerturn IE, Baay MF, Onsrud M, Ndhlovu PD, Taylor M. Genital schistosomiasis and its unacknowledged role on HIV transmission in the STD intervention studies. Int J STD AIDS. 2014; 25(10): 705-715. doi: 10.1177/0956462414523743
Kjetland EF, Ndhlovu PD, Mduluza T, et al. Simple clinical manifestations of genital Schistosomiasis heamatobium infection in rural Zimbabwean women. Am J Trop Med Hyg. 2005; 72(3): 311-319. Web site. http://www.ajtmh.org/content/72/3/311.long. Accessed August 29, 2016
Norseth HM, Ndhlovu PD, Kleppa E, et al. The colposcopi-caltas of schistosomiasis in the lower female genital tract based on studies in Malawi, Zimbabwe, Madagascar and South Africa. PloS Negl Trop Dis. 2014; 8(11): e3229. doi: 10.1371/journal. pntd.0003229
Boers KE, Sastrowijoto PH, Elzakker van EP, Hermans MP. Schistosomiasis of the uterus in a patient with dysmenorrhoea and menorrhagia. Eur J Obstet Gynecol Reprod Biol. 2003; 108(1): 106-108. doi: 10.1016/S0301-2115(02)00364-0
Hove MM, Javangwe TV. Female genital schistosomiasis: Pathological features and density infestation. Cent Afr J Med. 2014; 60(1-4): 13-16. Web site. http://www.ajol.info/index.php/ cajm/article/view/11792. Accessed August 29, 2016
Kjetland EF, Ndhlovu PD, Mduluza T, et al. The effects of genital schistosomahaematobium on human papillomavirus and the development of cervical neoplasia after five years in a Zim-babwean population. Eur J Gynaecol Oncol. 2010; 31(2): 169- 173. Web site. http://europepmc.org/abstract/med/20527233. Accessed August 29, 2016
Kjetland EF, Ndhlovu PD, Gomo E, et al. Association be-tween genital schistosomiasis and HIV in rural Zimbabwean women. AIDS. 2006; 20(4): 593-600.
Rollinson D. A wake up call for urinary schistosomiasis: Reconciling research effort with public health importance. Par-asitology. 2009; 136(12): 1593-1610.
Otieno-nyunya B. Tropical diseases can harm pregnancy. Netw Res Triangle Park NC. 1999; 19(2): 5-7.
Laroche J, Mottet N, Malincenco M, Gay C, Royer PY, Ri-ethmuller D. Successive ectopic pregnancies associated with tubal schistosomiasis in a French traveller. Pan Afr Med J. 2016; 23: 18. doi: 10.11604/pamj.2016.23.18.8845
Schanz A, Richter J, Beyer I, Baldus SE, Hess AP, Krues-sel JS. Genital schistosomiasis as a cause of female sterility and acute abdomen. Fertil Steril. 2010; 93(6): 2075.e7-e9. doi: 10.1016/j.fertnstert.2009.05.043
Batista TP, de Andrade JJ, Filho LA. Schistosoma mansoni: An unusual cause of ovarian pseudotumour. Arch Gynecol Ob-stet. 2010; 281(10): 141-143. doi: 10.1007/s00404-009-1091-3
Trainor-Moss S, Mutapi F. Schistosomiasis therapeutics: Whats in the pipeline? Expert Rev Clin Pharmacol. 2016; 9(2): 157-160. doi: 10.1586/17512433.2015.1102051
Holmen SD, Kleppa E, Lillebo K, et al. The first step toward diagnosing female genital schistosomiasis by computer image analysis. Am J Trop Med Hyg. 2015; 93(1): 80-86. doi: 10.4269/ ajtmh.15-0071
Randrianasolo BS, Jourdan PM, Ravoniarimbinina P, et al. Gynecological manifestations, histopathological findings, and schistosoma-specific polymerase chain reaction results among women with Schistosoma haematobium infection: A cross-sec-tional study in Madagascar. J Infect Dis. 2015; 212(2): 275-284. doi: 10.1093/infdis/jiv035
de Sousa CAP, Brigham T, Chasekwa B, et al. Dosing of pra-ziquantel by height in sub-Saharan Africa adults. Am J Trop Med Hyg. 2014; 90(4): 634-637. doi: 10.4269/ajtmh.13-0252
Christinet V, Lazdins-Helds JK, Stothard JR, Reinhard-Rupp J. Female genital schistosomiasis (FGS): From case reports to a call for concerted action against this neglected gynaecological disease. Int J Parasitol. 2016; 46(7): 395-404. doi: 10.1016/j. ijpara.2016.02.006
Yazdanbakhsh M, Deelder AM. Advances in schistoso-miasis research. Curr Opin Infect Dis. 1998; 11(5): 541-546. Web site. http://journals.lww.com/co-infectiousdiseases/ab-stract/1998/10000/advances_in_schistosomiasis_research.5. aspx. Accessed August 29, 2016
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