Coexistence of Tuberculosis and Metastatic Undifferentiated Carcinoma of Nasopharynx in Cervical Lymph Node

Crossmark: check for updates

Authors

  • Sameh Mezri ENT Department, Military Hospital of Tunis, Montfleury 1008,Tunisia
  • Sameh Sayhi Internal Department of Medicine, Military Hospital of Tunis, Montfleury 1008,Tunisia
  • Marwa Ben Amira ENT Department, Military Hospital of Tunis, Montfleury 1008,Tunisia
  • Issam Msakni Anatomopathology Department, Military Hospital of Tunis, Montfleury 1008,Tunisia
  • Besma Laabidi Anatomopathology Department, Military Hospital of Tunis, Montfleury 1008,Tunisia
  • Rania Ben M'hamed ENT Department, Military Hospital of Tunis, Montfleury 1008,Tunisia
  • Khemaies Akkeri ENT Department, Military Hospital of Tunis, Montfleury 1008,Tunisia

DOI:

https://doi.org/10.17140/OTLOJ-5-156

Keywords:

Lymph nodes tuberculosis, Undifferentiated nasopharyngeal carcinoma (UCNT), Lymph nodes metastasis

Abstract

The coexistence of a head and neck cancer and a lymph node tuberculosis is rarely described. The problem is essentially diagnos-tic. We report the case of a patient with cervical lymphadenopathy and non suspect swelliing of nasopharynx. Histopathological study of lymph node reveled an association of a tubercular adenitis and a metastasis of a squamous cell carcinoma.

References

Warthin AS. The coexistence of tuberculosis and carcino-ma of the mammary gland. Am J Med Sci. 1899; 118: 125. doi: 10.1097/00000441-189907000-00003

Gheriani H, Hafidh M, Smyth D, O'Dwyer T. Coexistent cervi-cal tuberculosis and metastatic squamous cell carcinoma in a single lymph node group: A diagnostic dilemma. Ear Nose Throat J. 2006; 85 :397-399. doi: 10.1177/014556130608500621

Barwad A, Gowda KK, Dey P. Co-existent of tuberculosis and squamous cell carcinoma in a lymph node diagnosed by fine needle aspiration cytology. Cytopathology. 2012; 23: 276-277. doi: 10.1111/j.1365-2303.2011.00878.x

Choukry C, Benouhoud J. Association de lymphadénites tuber-culeuses cervicales et de ganglions métastatiques cervicaux d’un cancer du nasopharynx (à propos d’un cas) [In: French]. Médecine Nucléaire. 2018; 42: 176-177. doi: 10.1016/j.mednuc.2018.03.116

Falagas ME, Kouranos VD, Athanassa Z, Kopterides P. Tuber-culosis and malignancy. Q J Med. 2010; 103: 461-487. doi: 10.1093/ qjmed/hcq068

Pandey M, Abraham EK, K C, Rajan B. Tuberculosis and meta-static carcinoma coexistence in axillary lymph node: A case report. World J Surg Oncol. 2003; 1: 3. doi: 10.1186/1477-7819-1-3

Centkowski P, Sawczuk-Chabin J, Prochorec M, Warzocha K. Hodgkin’s lymphoma and tuberculosis coexistence in cer-vical lymph nodes. Leuk Lymphoma. 2005; 46: 471-475. doi: 10.1080/10428190400019891

Caroppo D, Russo D, Merolla F, et al. A rare case of coexistence of metastasis from head and neck squamous cell carcinoma and tuberculosis within a neck lymph node. Diagn Pathol. 2015; 10: 197. doi: 10.1186/s13000-015-0430-x

Shin DM, Yang CS, Lee JY, et al. Mycobacterium tuberculosis lipoprotein-induced association of TLR2 with protein kinase C zeta in lipid rafts contributes to reactive oxygen species-dependent inflammatory signalling in macrophages. Cell Microbiol. 2008; 10: 1893-1905. doi: 10.1111/j.1462-5822.2008.01179.x

Kawanishi S, Hiraku Y, Pinlaor S, Ma N. Oxidative and nitrative DNA damage in animals and patients with inflammatory diseases in relation to inflammation-related carcinogenesis. Biol Chem. 2006; 387: 365-372. doi: 10.1515/BC.2006.049

Downloads

Published

2019-06-28

How to Cite

Sameh Mezri, Sameh Sayhi, Marwa Ben Amira, Issam Msakni, Besma Laabidi, Rania Ben M’hamed, & Khemaies Akkeri. (2019). Coexistence of Tuberculosis and Metastatic Undifferentiated Carcinoma of Nasopharynx in Cervical Lymph Node. Otolaryngology, 5(2), 26–28. https://doi.org/10.17140/OTLOJ-5-156

Similar Articles

You may also start an advanced similarity search for this article.