Prader-Willi Syndrome: A Case Report

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Authors

  • Erika Tayal MDS Department of Pedodontics and Preventive Dentistry, Sudha Rustagi College of Dental Sciences and Research, Faridabad, Haryana, India
  • KR Indushekar MDS Department of Pedodontics and Preventive Dentistry, Sudha Rustagi College of Dental Sciences and Research, Faridabad, Haryana, India
  • Bhavna G. Saraf MDS Department of Pedodontics and Preventive Dentistry, Sudha Rustagi College of Dental Sciences and Research, Faridabad, Haryana, India
  • Neha Sheoran MDS Department of Pedodontics and Preventive Dentistry, Sudha Rustagi College of Dental Sciences and Research, Faridabad, Haryana, India
  • Ashima Doda MDS Department of Pedodontics and Preventive Dentistry, Sudha Rustagi College of Dental Sciences and Research, Faridabad, Haryana, India

DOI:

https://doi.org/10.17140/PHOJ-1-104

Keywords:

Prader–Willi syndrome; Multisystemic genetic disorder; Hyperphagia; Obesity.

Abstract

Prader–Willi Syndrome (PWS) is a rare multi-systemic genetic disorder, in which 7 or some subset of genes on chromosome 15 are unexpressed or deleted on the paternal chromosome, resulting from failed expression of paternally inherited genes on chromosome 15q11–13. The majority of individuals with PWS (70%) have a paternally derived deletion of 15q11–13, Twenty-five percent have maternal disomy of chromosome 15 (an absence of the normally active paternally inherited genes on the long arm of chromosome 15) and 2-5% have imprinting defects (certain genes or groups of genes are expressed differently depending on the gender of the parent from which they were inherited).The main objective of this report is to further characterize the dental problems along with some of the general features of this syndrome and to emphasize the need of early involvement of dental practitioners for the overall management of these patients.

References

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Published

2016-01-31

How to Cite

Erika Tayal, KR Indushekar, Bhavna G. Saraf, Neha Sheoran, & Ashima Doda. (2016). Prader-Willi Syndrome: A Case Report. Public Health - Open Journal, 1(1), 12–15. https://doi.org/10.17140/PHOJ-1-104

Issue

Vol. 1 No. 1 (2016): Volume 1 Issue 1 2016

Section

Articles

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This work is licensed under a Creative Commons Attribution 4.0 International License.

All content published in Public Health - Open Journal (PHOJ) is licensed under the Creative Commons Attribution 4.0 International License (CC BY 4.0). This license allows anyone to copy, distribute, transmit, and adapt the work — including for commercial purposes — provided appropriate credit is given to the original author(s) and source.