Berry-Vegetable Nectar May Help to Diminish Hospital Visits and Service Reliefs in Conscripts during the High Risk Period of Upper Respiratory Tract Infections
DOI:
https://doi.org/10.17140/aftnsoj-1-111Keywords:
Anti-infective, Berries, Nutritional, Phytophenols, URTIAbstract
Phytophenols can counteract Upper Respiratory Tract Infections (URTI) by effect-ing on the microbes or by promoting immunity. At population level URTI has high economic significance. The aim of the study was to clarify if hospital visits or hospitalization or service reliefs from military service in conscripts could be diminished by phytophenol rich berry-veg-etable nectar supplementation during high URTI-risk period. The 6.5 week intervention was carried out during highest URTI-risk at winter. The intervention subjects were predominantly healthy male conscripts (n=188) in a four military companies. Controls were either from same four companies (n=359) or from eleven other companies (n=1597). All conscripts lived in a same garrison within similar environment and had similar exercise program and had similar diet ad libitum. Intervention subjects received three portions of berry-vegetable nectar in a day. Weekly visits at the hospital, service reliefs and days in the hospital per company were recorded. Effect by intervention was analyzed between intervention and control companies by repeated measures analysis of variance. Intervention effect by berry-vegetable nectar was seen as a lower amount of visits at the hospital clinic (p=0.002), and as a lower amount of reliefs from outdoor service (p=0.049), while significant effect on hospitalization or on releases from indoor and outdoor reliefs was not observed. We conclude that nutritional supplementation by-phytophenol rich berry-vegetable nectar may diminish hospital visits and reliefs from outdoor service in conscripts during high URTI-risk period.
References
Häkkinen SH, Kärenlampi SO, Heinonen M, Mykkänen HM, Törrönen RA. Content of the flavonols quercetin, myricetin, and kaempferol in 25 ediple berries. J Agric Food Chem. 1999; 47(6): 2274-2279. doi: 10.1021/jf9811065
Middleton E. Effect of plant flavonoids on immune and in-flammatory cell function. Adv Exp Med Biol. 1998; 439: 175- 182. doi: 10.1007/978-1-4615-5335-9_13
Pelzer LE, Guardia T, Osvaldo Juarez A, Guerreiro E. Acute and chronic anti-inflammatory effects of plant flavonoids. Farmaco. 1998; 30(6): 421-424. doi: 10.1016/S0014-827X(98)0 0046-9
Ivancheva S, Manolova N, Serkedjieva J, Dimov V, Ivanovs-ka N. Polyphenols from Bulgarian medical plants with anti-infectious activity. Basic Life Sci. 1992; 59: 717-728. doi: 10.1007/978-1-4615-3476-1_43
Sakanaka S, Aizawa M, Kim M, Yamamoto T. Inhibitory ef-fects of green tea polyphenols on growth and cellular adherence of an oral bacterium, Porphyromonas gingivalis. Biosci Biotech-nol Biochem. 1996; 60(5): 745-749. doi: 10.1271/bbb.60.745
Middleton E Jr, Kandaswami C. Effects of flavonoids on im-mune and inflammatory cell functions. Biochem Pharmacol. 1992; 17(6): 1167-1179. doi: 10.1016/0006-2952(92)90489-6
Nenonen MT, Helve TA, Rauma AL, Hänninen OO. Un-cooked, lactobacilli-rich, vegan food and rheumatoid arthri-tis. Br J Rheumatol. 1998; 37(3): 274-281. doi: 10.1093/ rheumatology/37.3.274
Hortal M, Benitez A, Contera M, Etorena P, Montano A, Meny M. A community-based study of acute respiratory tract infections in children in Uruguay. Rev Infect Dis. 1990; 12(S8): S966-S973.
Ponka A, Nurmi T, Salminen E, Nykyri E. Infections and other illnesses of children in day-care centers in Helsinki. Incidences and effects of home and day-care center variables. Infection. 1991; 19(4): 230-236. doi: 10.1007/BF01644951
Nieman DC, Pedersen BK. Exercise and immune function. Recent developments. Sports Med. 1999; 27(2): 73-80. doi: 10.2165/00007256-199927020-00001
Lehtoranta L, Kalima K, He L, et al. Specific probiotics and virological findings in symptomatic conscripts attending mili-tary service in Finland. J Clin Virol. 2014; 60(3): 276-281. doi: 10.1016/j.jcv.2014.03.021
Tompuri T, Hanninen O. Flavonoid rich nectar decreased up-per respiratory infections in training adolescents. International Review of the Armed Forces Medical Services. 2001; 74(4): 213- 216.
Glezen WP. Herd protection against influenza. J Clin Virol. 2006; 37(4): 237-243. doi: 10.1016/j.jcv.2006.08.020
Borg P, Fogelholm M, Vasankari T, Katila R, Tuomi T. Lack of effect of long-term antioxidant supplementation on the inci-dence of upper respiratory tract infections in athletes. Proceed-ings of the 5th Annual Congress of the European College of Sport Science. Jyväskylä, Finland, Europe: Gummerus; 2000: 171. 19-23.
Foo LY, Lu Y, Howell AB, Vorsa N. The structure of cranber-ry proanthocyanidins which inhibit adherence of uropathogenic P-fimbriated Escherichia coli in vitro. Phytochemistry. 2000; 54(2): 173-181. doi: 10.1016/S0031-9422(99)00573-7
Nakahara K, Kawabata S, Ono H, et al. Inhibitory effect of oolong tea polyphenols on glycosyl transferases of mutans Streptococci. Appl Environ Microbiol. 1993; 59(4): 968-973.
Nakayama M, Suzuki K, Toda M, Okubo S, Hara Y, Shi-mamura T. Inhibition of the infectivity of influenza virus by tea polyphenols. Antiviral Res. 1993; 21(4): 289-299. doi: 10.1016/0166-3542(93)90008-7
Reynolds HY. Respiratory infections may reflect deficiencies in host defence mechanisms. Dis Mon. 1985; 31(2): 1-98. doi: 10.1016/0011-5029(85)90010-0
Tagashira M, Uchiyama K, Yoshimura T, Shirota M, Uemit-su N. Inhibition by hop bract polyphenols of cellular adherence and water-insoluble glucan synthesis of mutants streptococci. Biosci Biotechnol Biochem. 1997; 61(2): 332-335. doi: 10.1271/ bbb.61.332
Chung KT, Wong TY, Wei CI, Huang YW, Lin Y. Tannins and human health: A review. Crit Rev Food Sci Nutr. 1998; 38(6): 421-464. doi: 10.1080/10408699891274273
Hollman PC, Katan MB. Absorption, metabolism and health effects of dietary flavonoids in man. Biomed Pharmacother. 1997; 51(8): 305-310.
Dekkers JC, van Doornen LJ, Kemper HC. The role of an-tioxidant vitamins and enzymes in the prevention of exercise-induced muscle damage. Sports Med. 1996; 21(3): 213-238. doi: 10.2165/00007256-199621030-00005
Wruss J, Lanzerstorfer P, Huemer S, et al. Differences in pharmacokinetics of apple polyphenols after standardized oral consumption of unprocessed apple juice. Nutr J. 2015; 14(1): 32. doi: 10.1186/s12937-015-0018-z
Sakagami H, Oi T, Satoh K. Prevention of oral diseases by polyphenols (review). In Vivo. 1999; 13(2): 155-171.
Fendrick AM, Monto AS, Nightengale B, Sarnes M. The economic burden of non–influenza-related viral respiratory tract infection in the United States. Arch Intern Med. 2003; 163(4): 487-494. doi: 10.1001/archinte.163.4.487
Published
How to Cite
Issue
Section
License

This work is licensed under a Creative Commons Attribution 4.0 International License.
All content published in Advances in Food Technology and Nutrition Sciences (AFTNS) is licensed under the Creative Commons Attribution 4.0 International License (CC BY 4.0). This license allows anyone to copy, distribute, transmit, and adapt the work — including for commercial purposes — provided appropriate credit is given to the original author(s) and source.