Recent Advances in Fibro-blast Growth Factor-23 Functions
DOI:
https://doi.org/10.17140/NPOJ-1-110Keywords:
controversial, coexpressions, fibroblastAbstract
During the past decade a lot of work has been done to better understand the roles
of fibroblast growth factor-23 (FGF-23); a relatively newly discovered endocrine hormone,
in multiple organ systems in the body. This review focuses on expressions of FGF-23, coexpressions of α-Klotho and FGF receptors, and FGF-23 mediated end-organ effects in the
physiological and pathological conditions. We also discuss the controversial reports regarding
α-Klotho-dependent and α-Klotho-independent functions of FGF-23.
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