Crosstalk between Autophagy and Obesity: Potential Use of Avian Model

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Authors

  • Alissa Piekarski Center of Excellence for Poultry Science, University of Arkansas, Fayetteville AR 72701, USA
  • Elizabeth Greene Center of Excellence for Poultry Science, University of Arkansas, Fayetteville AR 72701, USA
  • Nicholas B. Anthony Center of Excellence for Poultry Science, University of Arkansas, Fayetteville AR 72701, USA
  • Walter Bottje Center of Excellence for Poultry Science, University of Arkansas, Fayetteville AR 72701, USA
  • Sami Dridi Center of Excellence for Poultry Science, University of Arkansas, Fayetteville AR 72701, USA

DOI:

https://doi.org/10.17140/aftnsoj-1-106

Keywords:

Autophagy, Obesity, Avian species

Abstract

Autophagy, a self-eating mechanism for recycling cellular constituents, is essential for maintaining cellular homeostasis and its malfunction is associated with diverse diseases including neurodegeneration, cancer, immunity and metabolic syndrome. Human Obesity is a devastating multifactorial disease with continuous increasing prevalence and, thus, there is a need for more extensive research using several experimental models to understand its underlying molecular mechanisms. Emerging evidence indicates a key role of autophagy in the development of obesity and has been a focus of research interest in recent years. This review will briefly describe the autophagy processes and provide insight into metabolic characteristics of avian species that make birds a model of choice for investigation of autophagy particularly with respect to obesity.

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Published

2015-02-13

How to Cite

Alissa Piekarski, Elizabeth Greene, Nicholas B. Anthony, Walter Bottje, & Sami Dridi. (2015). Crosstalk between Autophagy and Obesity: Potential Use of Avian Model. Advances in Food Technology and Nutrition Sciences, 1(1), 32–37. https://doi.org/10.17140/aftnsoj-1-106

Issue

Vol. 1 No. 1 (2015): Volume 1 Issue 1 2015

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